Evidence map›Paper›PMID 35745241›Full record

ArticleNutrients2022

Consumption of Dietary Fiber with Different Physicochemical Properties during Late Pregnancy Alters the Gut Microbiota and Relieves Constipation in Sow Model.

Dongdong Lu, Yu Pi, Hao Ye, Yujun Wu, Yu Bai, Shuai Lian, Dandan Han, Dongjiao Ni, Xinhua Zou, Jinbiao Zhao and 4 more

Open access · goldAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. The Effects of Vitamin DAnimals : an open access journal from MDPI · 2026
    Article
  5. Review
  6. Effects ofMicrobiology spectrum · 2026
    Article
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  8. Review
  9. Article
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  11. Article
  12. Article
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  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Modulation of the gut microbiota by dietary intervention withBioscience of microbiota, food and health · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Dongdong LuState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Yu PiState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0003-1320-0290
Hao YeAdaptation Physiology Group, Department of Animal Sciences, Wageningen University, 6700 AH Wageningen, The Netherlands.
Yujun WuState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Yu BaiState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Shuai LianState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Dandan HanState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Dongjiao NiKey Laboratory of Biological Feed, Ministry of Agriculture and Rural Affairs, Boen Biotechnology Co., Ltd., Ganzhou 341000, China.
Xinhua ZouKey Laboratory of Biological Feed, Ministry of Agriculture and Rural Affairs, Boen Biotechnology Co., Ltd., Ganzhou 341000, China.
Jinbiao ZhaoState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Shuai ZhangState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-5435-2640
Bas KempAdaptation Physiology Group, Department of Animal Sciences, Wageningen University, 6700 AH Wageningen, The Netherlands.
Nicoline SoedeAdaptation Physiology Group, Department of Animal Sciences, Wageningen University, 6700 AH Wageningen, The Netherlands.ORCID 0000-0003-0296-886X
Junjun WangState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-9427-3824
China Agricultural University · CNMinistry of Agriculture and Rural Affairs · CNWageningen University & Research · NL

Funding

111 Project B16044China Agriculture Research System CARS-35China Postdoctoral Science Foundation 2020M682102China Scholarship Council 201913043Key-Area Research and Development Program of Guangdong Province 2019B020218001National Key Research and Development Program of China 2021YDF1300201National Natural Science Foundation of China 31630074National Natural Science Foundation of China 31902170National Natural Science Foundation of China 31972596National Natural Science Foundation of China 32002189
6 · The paper itself

Abstract

Constipation is a common problem in sows and women during late pregnancy. Dietary fiber has potential in the regulation of intestinal microbiota, thereby promoting intestinal motility and reducing constipation. However, the effects of fibers with different physicochemical properties on intestinal microbe and constipation during late pregnancy have not been fully explored. In this study, a total of 80 sows were randomly allocated to control and one of three dietary fiber treatments from day 85 of gestation to delivery: LIG (lignocellulose), PRS (resistant starch), and KON (konjaku flour). Results showed that the defecation frequency and fecal consistency scores were highest in PRS. PRS and KON significantly increased the level of gut motility regulatory factors, 5-hydroxytryptamine (5-HT), motilin (MTL), and acetylcholinesterase (AChE) in serum. Moreover, PRS and KON promoted the IL-10 level and reduced the TNF-α level in serum. Furthermore, maternal PRS and KON supplementation significantly reduced the number of stillborn piglets. Microbial sequencing analysis showed that PRS and KON increased short-chain fatty acids (SCFAs)-producing genera

Indexed as

Gastrointestinal MicrobiomeAcetylcholinesteraseAnimalsBacteriaButyratesConstipationDietary FiberFecesFemalePregnancySerotoninSwineAcetylcholinesteraseButyratesDietary FiberSerotonindefecation frequencydietary fiberdifferent physicochemical propertiesintestinal motilitylate pregnancyTuricibacter

Identifiers

PMID35745241
PMCPMC9229973
OpenAlexW4283079753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.