Evidence map›Paper›PMID 35745234›Full record

ArticleNutrients2022

Consumption of Yoghurt and Other Dairy Products and Risk of Colorectal Cancer in Iran: The IROPICAN Study.

Giulia Collatuzzo, Monireh Sadat Seyyedsalehi, Abbas Rezaeianzadeh, Maryam Marzban, Hamideh Rashidian, Maryam Hadji, Farin Kamangar, Arash Etemadi, Eero Pukkala, Kazem Zendehdel and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  6. Observational
  7. Article
  8. Article
  9. Opium use and gastrointestinal cancers: a systematic review and meta-analysis study.Gastroenterology and hepatology from bed to bench · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 4 countries.

Giulia CollatuzzoDepartment of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-2309-7365
Monireh Sadat SeyyedsalehiDepartment of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.
Abbas RezaeianzadehColorectal Research Center, Shiraz University of Medical Sciences, Shiraz 7146864685, Iran.
Maryam MarzbanDepartment of Public Health, School of Public Health, Bushehr University of Medical Science, Bushehr 7514763448, Iran.
Hamideh RashidianCancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran 1416634793, Iran.
Maryam HadjiCancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran 1416634793, Iran.ORCID 0000-0001-5486-7513
Farin KamangarDepartment of Biology, School of Computer, Mathematical, and Natural Sciences, Morgan State University, Baltimore, MD 21251, USA.
Arash EtemadiDigestive Oncology Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran 1416634793, Iran.
Eero PukkalaHealth Sciences Unit, Faculty of Social Sciences, Tampere University, 33100 Tampere, Finland.
Kazem ZendehdelCancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran 1416634793, Iran.
Paolo BoffettaDepartment of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-3811-2791
Tehran University of Medical Sciences · IRTampere University · FIBushehr University of Medical Sciences · IRMorgan State University · USShariati Hospital · IRShiraz University of Medical Sciences · IRStony Brook University · USUniversity of Bologna · IT

Funding

Upper Gastrointestinal Cancer StudiesZIACP000185 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ABNET, CHRISTIAN · 2009 to 2025
$25.6M
National Institute of Medical Research Development (NIMAD) (Code: IR.NIMAD.REC.1394.027). IR.NIMAD.REC.1394.027
6 · The paper itself

Abstract

backgroundThere is evidence of an inverse association between yoghurt intake and risk of colorectal cancer (CRC). We aimed at investigating the association between the intake of yoghurt and other dairy foods consumed in Iran and CRC risk.

methodsOur analysis included 4070 subjects within the IROPICAN (Iran Study of Opium and Cancer) study. Detailed information was collected by the use of validated questionnaires. We estimated adjusted odds ratios (OR) and 95% confidence intervals (CI) for the association between the intake of total dairy products, and, separately, of yoghurt, milk, cheese, kashk, dough, cream, ice cream, and other milk products, and CRC using unconditional logistic regression analyses. The intake was categorized in tertiles.

resultsOverall, we analyzed 865 cases and 3205 controls. Total dairy products intake was not associated with CRC. The OR for one tertile increase (OR_T) in yoghurt intake was 0.97 (95% CI 0.87-1.08) for CRC and 0.66 (95% CI 0.52-0.84) for proximal colon cancer. Cream intake was associated with CRC (OR_T3 = 1.33, 95% CI 1.08-1.64), colon (OR_T3 = 1.37, 95% CI 1.03-1.81), and proximal cancer (OR_T3 = 1.29, 95% CI 1.04-1.61). The OR of distal colon cancer for ice cream intake was 0.59 (95% CI 0.43-0.82). Other dairy products were not associated with CRC risk.

Indexed as

CheeseColonic NeoplasmsColorectal NeoplasmsAnimalsDairy ProductsDietHumansIranMilkRisk FactorsYogurtcoloncolorectal cancerdairy productsdietnutrition epidemiologyyoghurt

Identifiers

PMID35745234
PMCPMC9228368
OpenAlexW4283071147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.