Evidence map›Paper›PMID 35745156›Full record

ReviewNutrients2022

A Cross-Talk between Diet and the Oral Microbiome: Balance of Nutrition on Inflammation and Immune System's Response during Periodontitis.

Simona Santonocito, Amerigo Giudice, Alessandro Polizzi, Giuseppe Troiano, Emanuele Maria Merlo, Rossana Sclafani, Giuseppe Grosso, Gaetano Isola

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 1 pooled it
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 1 synthesis or guideline pooled it, 134 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Characterizing the supragingival microbiome of healthy pregnant women.Frontiers in cellular and infection microbiology · 2022
    Trial
  4. Article
  5. Review
  6. The Oral Microbiome: A Silent Contributor to Systemic Health and Disease National Institutes of Health 2024 Workshop.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  7. Review
  8. Observational
  9. [The Oral Microbiome: Maintenance of Homeostasis, Disease Associations, and Mechanisms of Pathogenesis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Fimbriae potentiateCurrent research in microbial sciences · 2026
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Simona SantonocitoUnit of Periodontology, Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, 95124 Catania, Italy.ORCID 0000-0003-1020-4341
Amerigo GiudiceUnit of Dentistry, Department of Health Sciences, University of Catanzaro "Magna Graecia", 88100 Catanzaro, Italy.ORCID 0000-0001-9374-0566
Alessandro PolizziUnit of Periodontology, Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, 95124 Catania, Italy.ORCID 0000-0001-6717-8899
Giuseppe TroianoDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0001-5647-4414
Emanuele Maria MerloDepartment of Human and Pediatric Pathology "Gaetano Barresi", University of Messina, 98122 Messina, Italy.
Rossana SclafaniUnit of Periodontology, Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, 95124 Catania, Italy.ORCID 0000-0003-4064-6984
Giuseppe GrossoDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-3930-5285
Gaetano IsolaUnit of Periodontology, Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, 95124 Catania, Italy.ORCID 0000-0003-4267-6992
University of Catania · ITMagna Graecia University · ITUniversity of Foggia · ITUniversity of Messina · IT

Funding

University of Catania PIACERI 2020-2022
6 · The paper itself

Abstract

Over the last few decades, studies on the oral microbiome have increased awareness that the balance between the host and the microbial species that coexist in it is essential for oral health at all stages of life. However, this balance is extremely difficult to maintain, and many factors can disrupt it: general eating habits, sugar consumption, tobacco smoking, oral hygiene, and use of antibiotics and other antimicrobials. It is now known that alterations in the oral microbiota are responsible for developing and promoting many oral diseases, including periodontal disease. In this context, diet is an area for further investigation as it has been observed that the intake of particular foods, such as farmed animal meat, dairy products, refined vegetable oils, and processed cereals, affects the composition of the microbiota, leading to an increased representation of acid-producing and acid-tolerant organisms and periodontal pathogens. However, little is known about the influence of diet on the oral microbiome and the creation of a suitable microenvironment for the development of periodontal disease. The aim of the present study is to evaluate current knowledge on the role of diet in the oral dysbiosis underlying periodontal disease.

Indexed as

MicrobiotaPeriodontal DiseasesPeriodontitisAnimalsDietDysbiosisImmune SystemInflammationdietimmune responsemacronutrientsmicrobiomemicronutrientsnutrientsoral dysbiosisoral healthperiodontitis

Identifiers

PMID35745156
PMCPMC9227938
OpenAlexW4282561604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.