Evidence map›Paper›PMID 35745100›Full record

ArticleNutrients2022

Impact of Physical Activity Differences Due to COVID-19 Pandemic Lockdown on Non-Alcoholic Fatty Liver Parameters in Adults with Metabolic Syndrome.

Catalina M Mascaró, Cristina Bouzas, Sofía Montemayor, Silvia García, David Mateos, Miguel Casares, Cristina Gómez, Lucía Ugarriza, Pere-Antoni Borràs, J Alfredo Martínez and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. COVID-19 and Fatty Liver Disorders.Journal of clinical medicine · 2023
    Review
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Catalina M MascaróResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.
Cristina BouzasResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.ORCID 0000-0002-1407-8461
Sofía MontemayorResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.ORCID 0000-0001-7833-2118
Silvia GarcíaResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.
David MateosResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.
Miguel CasaresRadiodiagnosis Service, Red Asistencial Juaneda, 07011 Palma de Mallorca, Spain.
Cristina GómezResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.ORCID 0000-0002-9776-4730
Lucía UgarrizaResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.
Pere-Antoni BorràsArea of Physical Education and Sports, Department of Pedagogy and Specific Didactics, University of the Balearic Islands, 07122 Palma de Mallorca, Spain.ORCID 0000-0001-6793-7592
J Alfredo MartínezCardiometabolics Precision Nutrition Program, IMDEA Food, CEI UAM-CSIC, 28049 Madrid, Spain.ORCID 0000-0001-5218-6941
Josep A TurResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.ORCID 0000-0002-6940-0761
Health Research Institute of the Balearic Islands · ESInstituto de Salud Carlos III · ESMadrid Institute for Advanced Studies · ESResearch Institute of Health Sciences · ESUniversitat de les Illes Balears · ES

Funding

European Regional Development Fund N/AFundació La Marató TV3 201630.10IDISBA FOLIUM, PRIMUS, SYNERGIA, and LIBERIInstituto de Salud Carlos III CIBEROBN CB12/03/30038, and Proyecto Intramural CIBER OBN18PI03Spanish Ministry of Education FPU PhD Grant
6 · The paper itself

Abstract

backgroundA Mediterranean lifestyle with a Mediterranean diet and regular physical activity (PA) improves metabolic syndrome (MetS) characteristics and non-alcoholic fatty liver disease (NAFLD). The COVID-19 pandemic stopped healthy habits and increased NAFLD progression.

objectivesTo assess how PA differences due to COVID-19 lockdown affected NAFLD parameters in adults with MetS.

designLongitudinal 2-year analysis of data obtained between COVID-19 pre- and post-lockdown in a parallel-group randomized trial (n = 57, aged 40-60 years old, with MetS and NAFLD).

methodsNAFLD status and related parameters were assessed by magnetic resonance imaging (MRI), blood collection analysis and related indexes. PA and fitness status were assessed by an Alpha-Fit test battery, accelerometers, validated Minnesota questionnaire and functional fitness score. During lockdown, study personnel telephoned patients to motivate them. Participants were grouped according to PA levels.

resultsThe low PA group improved its fitness score tests (0.2) after lockdown more than the medium PA group, and it decreased its sedentary activity (-48.7 min/day), increased light (20.9 min/day) and moderate (32.3 min/day) PA intensities and improved sleep efficiency (0.6%) in comparison with the medium and high PA groups. The high PA group increased its steps per day more than the other groups. The low PA group was the only group that decreased its gamma glutamyl transferase (GGT) levels (-17.0 U/L). All groups increased their fatty liver index (FLI) after lockdown, but the medium PA group increased its FLI more than the low PA group. Participants in the high PA group decreased their HDL-cholesterol levels more than participants in the medium PA group (-0.4 mg/dL).

conclusionsStopping regular PA together with an unhealthy lifestyle leads to a worsening of MetS and NAFLD. COVID-19 lockdown induced a decrease in PA in more active people, but inactive people increased their PA levels. Motivation seemed to be very important during lockdown.

Indexed as

COVID-19ExerciseMetabolic SyndromeNon-alcoholic Fatty Liver DiseaseAdultCommunicable Disease ControlHumansLongitudinal StudiesMiddle AgedPandemicsRandomized Controlled Trials as TopicCOVID-19 lockdownfitnessMediterranean dietMediterranean lifestylemetabolic syndromenon-alcoholic fatty liver diseasephysical activity

Identifiers

PMID35745100
PMCPMC9229383
OpenAlexW4282829762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.