Evidence map›Paper›PMID 35745076›Full record

ArticleMolecules (Basel, Switzerland)2022

Quantification of Salicylates and Flavonoids in Poplar Bark and Leaves Based on IR, NIR, and Raman Spectra.

Sylwester Mazurek, Maciej Włodarczyk, Sonia Pielorz, Piotr Okińczyc, Piotr M Kuś, Gabriela Długosz, Diana Vidal-Yañez, Roman Szostak

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Sylwester MazurekDepartment of Chemistry, University of Wrocław, 14 F. Joliot-Curie, 50-383 Wrocław, Poland.ORCID 0000-0002-8096-5229
Maciej WłodarczykDepartment of Pharmacognosy and Herbal Medicines, Faculty of Pharmacy, Wroclaw Medical University, 211a Borowska, 50-556 Wrocław, Poland.ORCID 0000-0002-8437-2711
Sonia PielorzDepartment of Chemistry, University of Wrocław, 14 F. Joliot-Curie, 50-383 Wrocław, Poland.
Piotr OkińczycDepartment of Pharmacognosy and Herbal Medicines, Faculty of Pharmacy, Wroclaw Medical University, 211a Borowska, 50-556 Wrocław, Poland.ORCID 0000-0001-5795-8605
Piotr M KuśDepartment of Pharmacognosy and Herbal Medicines, Faculty of Pharmacy, Wroclaw Medical University, 211a Borowska, 50-556 Wrocław, Poland.ORCID 0000-0002-7368-1076
Gabriela DługoszDepartment of Pharmacognosy and Herbal Medicines, Faculty of Pharmacy, Wroclaw Medical University, 211a Borowska, 50-556 Wrocław, Poland.
Diana Vidal-YañezDepartment of Pharmacognosy and Herbal Medicines, Faculty of Pharmacy, Wroclaw Medical University, 211a Borowska, 50-556 Wrocław, Poland.
Roman SzostakDepartment of Chemistry, University of Wrocław, 14 F. Joliot-Curie, 50-383 Wrocław, Poland.ORCID 0000-0002-5436-7284
Wroclaw Medical University · PLUniversity of Wrocław · PL

Funding

Wroclaw Medical University SUB.D110.21.101
6 · The paper itself

Abstract

Poplar bark and leaves can be an attractive source of salicylates and other biologically active compounds used in medicine. However, the biochemical variability of poplar material requires a standardization prior to processing. The official analytical protocols used in the pharmaceutical industry rely on the extraction of active compounds, which makes their determination long and costly. An analysis of plant materials in their native state can be performed using vibrational spectroscopy. This paper presents for the first time a comparison of diffuse reflectance in the near- and mid-infrared regions, attenuated total reflection, and Raman spectroscopy used for the simultaneous determination of salicylates and flavonoids in poplar bark and leaves. Based on 185 spectra of various poplar species and hybrid powdered samples, partial least squares regression models, characterized by the relative standard errors of prediction in the 4.5-9.9% range for both calibration and validation sets, were developed. These models allow for fast and precise quantification of the studied active compounds in poplar bark and leaves without any chemical sample treatment.

Indexed as

FlavonoidsSalicylatesCalibrationLeast-Squares AnalysisPlant BarkPlant LeavesFlavonoidsSalicylatesflavonoidsmultivariate analysispoplarsalicylatesvibrational spectroscopy

Identifiers

PMID35745076
PMCPMC9229158
OpenAlexW4283209258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.