Evidence map›Paper›PMID 35745011›Full record

ArticleMolecules (Basel, Switzerland)2022

Antibacterial and Oxidative Stress-Protective Effects of Five Monoterpenes from Softwood.

Riina Muilu-Mäkelä, Ulla Aapola, Jenni Tienaho, Hannu Uusitalo, Tytti Sarjala

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Essential Oil ofPlants (Basel, Switzerland) · 2026
    Review
  5. Selective bioactive effects ofFrontiers in pharmacology · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. The Controversial Roles of Areca Nut: Medicine or Toxin?International journal of molecular sciences · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Riina Muilu-MäkeläProduction Systems Unit, Natural Resources Institute Finland, FI-00791 Helsinki, Finland.
Ulla AapolaDepartment of Ophthalmology, Tampere University, FI-33520 Tampere, Finland.ORCID 0000-0001-7691-3170
Jenni TienahoProduction Systems Unit, Natural Resources Institute Finland, FI-00791 Helsinki, Finland.ORCID 0000-0002-7089-7832
Hannu UusitaloDepartment of Ophthalmology, Tampere University, FI-33520 Tampere, Finland.
Tytti SarjalaProduction Systems Unit, Natural Resources Institute Finland, FI-00791 Helsinki, Finland.
Natural Resources Institute Finland · FITampere University · FI

Funding

Environmental Ministry of Finland VN/2884/2019European Regional Development Fund A71142Strategic internal Funding of Natural Resources Institute Finland 41007-00096900
6 · The paper itself

Abstract

Volatile organic compounds (VOC) affect the quality of indoor air. Terpenes and especially monoterpenes are the main molecules emitted from softwood material (coniferous species), which is widely used in construction. The corneal epithelium is one of the first human membranes to encounter VOCs in the air. Moreover, the industrial use of pleasant-scented monoterpenes in cosmetics, food, and detergents exposes people to monoterpenes in their daily lives. In the present study, the health effective properties of five monoterpenes from softwood were tested; cytotoxicity and oxidative stress-protective effects of α- and β-pinenes, R- and S-limonene, and 3-carene were tested in a human corneal epithelial (HCE) cell model system and with two additional in vitro antioxidant tests: oxygen radical absorbance capacity (ORAC) and hydrogen peroxide (H

Indexed as

MonoterpenesOils, VolatileAnti-Bacterial AgentsAntioxidantsEscherichia coliHumansHydrogen PeroxideMicrobial Sensitivity TestsOxidative StressAnti-Bacterial AgentsAntioxidantsHydrogen PeroxideMonoterpenesOils, Volatileantibacterial propertiesantioxidantsbiosensorsHCE cellsmonoterpenessoft wood material

Identifiers

PMID35745011
PMCPMC9230896
OpenAlexW4283025906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.