Evidence map›Paper›PMID 35744986›Full record

ReviewMolecules (Basel, Switzerland)2022

Exploring the Phytochemicals and Anti-Cancer Potential of the Members of Fabaceae Family: A Comprehensive Review.

Muhammad Usman, Waseem Razzaq Khan, Nousheen Yousaf, Seemab Akram, Ghulam Murtaza, Kamziah Abdul Kudus, Allah Ditta, Zamri Rosli, Muhammad Nawaz Rajpar, Mohd Nazre

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 97 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Nutraceutical Potential ofMetabolites · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Metabolite Profiling ofPlants (Basel, Switzerland) · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Muhammad UsmanDepartment of Botany, Government College University Lahore, Katchery Road, Lahore 54000, Pakistan.ORCID 0000-0002-5923-5272
Waseem Razzaq KhanInstitut Ekosains Borneo, Universiti Putra Malaysia Kampus Bintulu, Bintulu 97008, Malaysia.ORCID 0000-0002-5981-2105
Nousheen YousafDepartment of Botany, Government College University Lahore, Katchery Road, Lahore 54000, Pakistan.ORCID 0000-0003-0471-5882
Seemab AkramDepartment of Biology, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Ghulam MurtazaFaculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.ORCID 0000-0001-7369-6107
Kamziah Abdul KudusDepartment of Forestry Science and Biodiversity, Faculty of Forestry and Environment, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0001-6694-984X
Allah DittaDepartment of Environmental Sciences, Shaheed Benazir Bhutto University Sheringal, Upper Dir 18000, Pakistan.ORCID 0000-0003-1745-4757
Zamri RosliDepartment of Forestry Science, Faculty of Agriculture and Forestry Sciences, Universiti Putra Malaysia Kampus Bintulu, Bintulu 97008, Malaysia.
Muhammad Nawaz RajparDepartment of Forestry, Faculty of Life Sciences, SBBU Sheringal, Dir Upper 18000, Pakistan.ORCID 0000-0002-6881-7346
Mohd NazreDepartment of Forestry Science and Biodiversity, Faculty of Forestry and Environment, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0001-7685-1184
Universiti Putra Malaysia · MYGovernment College University, Lahore · PKShaheed Benazir Bhutto University · PKKunming University of Science and Technology · CN

Funding

Universiti Putra Malaysia 5540232
6 · The paper itself

Abstract

Cancer is the second-ranked disease and a cause of death for millions of people around the world despite many kinds of available treatments. Phytochemicals are considered a vital source of cancer-inhibiting drugs and utilize specific mechanisms including carcinogen inactivation, the induction of cell cycle arrest, anti-oxidant stress, apoptosis, and regulation of the immune system. Family Fabaceae is the second most diverse family in the plant kingdom, and species of the family are widely distributed across the world. The species of the Fabaceae family are rich in phytochemicals (flavonoids, lectins, saponins, alkaloids, carotenoids, and phenolic acids), which exhibit a variety of health benefits, especially anti-cancer properties; therefore, exploration of the phytochemicals present in various members of this family is crucial. These phytochemicals of the Fabaceae family have not been explored in a better way yet; therefore, this review is an effort to summarize all the possible information related to the phytochemical status of the Fabaceae family and their anti-cancer properties. Moreover, various research gaps have been identified with directions for future research.

Indexed as

FabaceaeNeoplasmsAntioxidantsHumansPhytochemicalsPlant ExtractsAntioxidantsPhytochemicalsPlant Extractsanti-oxidantsapoptosiscancercancer treatmentFabaceaephytochemicals

Identifiers

PMID35744986
PMCPMC9230627
OpenAlexW4283069912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.