Evidence map›Paper›PMID 35744948›Full record

ArticleMolecules (Basel, Switzerland)2022

The Denaturant- and Mutation-Induced Disassembly of

Victor Marchenkov, Natalia Lekontseva, Natalia Marchenko, Ivan Kashparov, Victoriia Murina, Alexey Nikulin, Vladimir Filimonov, Gennady Semisotnov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Victor MarchenkovInstitute of Protein Research, Russian Academy of Sciences, Institutskaya Street 4, 142290 Pushchino, Russia.
Natalia LekontsevaInstitute of Protein Research, Russian Academy of Sciences, Institutskaya Street 4, 142290 Pushchino, Russia.
Natalia MarchenkoInstitute of Protein Research, Russian Academy of Sciences, Institutskaya Street 4, 142290 Pushchino, Russia.ORCID 0000-0003-2967-4677
Ivan KashparovInstitute of Protein Research, Russian Academy of Sciences, Institutskaya Street 4, 142290 Pushchino, Russia.
Victoriia MurinaInstitute of Protein Research, Russian Academy of Sciences, Institutskaya Street 4, 142290 Pushchino, Russia.
Alexey NikulinInstitute of Protein Research, Russian Academy of Sciences, Institutskaya Street 4, 142290 Pushchino, Russia.
Vladimir FilimonovInstitute of Protein Research, Russian Academy of Sciences, Institutskaya Street 4, 142290 Pushchino, Russia.
Gennady SemisotnovInstitute of Protein Research, Russian Academy of Sciences, Institutskaya Street 4, 142290 Pushchino, Russia.ORCID 0000-0003-4311-3884
Institute of Protein Research · RU

Funding

Russian Science Foundation 22-24-00934
6 · The paper itself

Abstract

Although oligomeric proteins are predominant in cells, their folding is poorly studied at present. This work is focused on the denaturant- and mutation-induced disassembly of the hexameric mutant Y55W of the Qβ host factor (Hfq) from mesophilic

Indexed as

Protein FoldingPseudomonas aeruginosaCircular DichroismMutationProtein DenaturationProtein Structure, SecondaryThermodynamicsTryptophanUreaTryptophanUreafluorescenceHfq hexamermutationsthermodynamicsunfolding intermediates

Identifiers

PMID35744948
PMCPMC9228748
OpenAlexW4282935455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.