Evidence map›Paper›PMID 35744938›Full record

ArticleMolecules (Basel, Switzerland)2022

Phytochemical Study and Antiglioblastoma Activity Assessment of

Eva María Domínguez-Martín, Mariana Magalhães, Ana María Díaz-Lanza, Mário P Marques, Salvatore Princiotto, Ana M Gómez, Thomas Efferth, Célia Cabral, Patricia Rijo

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Plants (Basel, Switzerland) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eva María Domínguez-MartínCenter for Research in Biosciences & Health Technologies (CBIOS), Universidade Lusófona de Humanidades e Tecnologias, Campo Grande 376, 1749-024 Lisbon, Portugal.ORCID 0000-0002-7884-4292
Mariana MagalhãesPhD Programme in Experimental Biology and Biomedicine, Institute for Interdisciplinary Research (IIIUC), University of Coimbra, Casa Costa Alemão, 3030-789 Coimbra, Portugal.ORCID 0000-0002-1874-1611
Ana María Díaz-LanzaNew Antitumor Compounds-Toxic Action on Leukemia Cells Research Group, Pharmacology Area (Pharmacognosy Laboratory), Department of Biomedical Sciences, Faculty of Pharmacy, University of Alcalá de Henares, Ctra. A2, Km 33.100-Campus Universitario, Alcalá de Henares, 28805 Madrid, Spain.ORCID 0000-0002-4216-3997
Mário P MarquesFaculty of Medicine, Clinic Academic Center of Coimbra (CACC), Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, 3000-548 Coimbra, Portugal.
Salvatore PrinciottoCenter for Research in Biosciences & Health Technologies (CBIOS), Universidade Lusófona de Humanidades e Tecnologias, Campo Grande 376, 1749-024 Lisbon, Portugal.ORCID 0000-0003-3440-8373
Ana M GómezInstituto de Química Orgánica, IQOG-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0002-8703-3360
Thomas EfferthDepartment of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany.ORCID 0000-0002-2637-1681
Célia CabralFaculty of Medicine, Clinic Academic Center of Coimbra (CACC), Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0003-4562-6683
Patricia RijoCenter for Research in Biosciences & Health Technologies (CBIOS), Universidade Lusófona de Humanidades e Tecnologias, Campo Grande 376, 1749-024 Lisbon, Portugal.ORCID 0000-0001-7992-8343

Funding

Fundação para a Ciência e Tecnologia PEst-OE/SAU/UI4013/2014, UID/DTP/04567/2016, UIDB/04567/2020, UIDP/04567/2020, UIDB/04539/2020, UIDP/04539/2020ILIND COFAC/ILIND/CBIOS/1/2020Spanish Ministerio de Ciencia e Innovación RTI2018-094862-B-100
6 · The paper itself

Abstract

Glioblastoma (GB) is the most malignant form of primary astrocytoma, accounting for more than 60% of all brain tumors in adults. Nowadays, due to the development of multidrug resistance causing relapses to the current treatments and the development of severe side effects resulting in reduced survival rates, new therapeutic approaches are needed. The genus

Indexed as

Brain NeoplasmsPlectranthusAbietanesHumansPhytochemicalsPlant ExtractsTissue DistributionAbietanesPhytochemicalsPlant ExtractscancerditerpenesglioblastomaLamiaceaephytochemicalPlectranthusroyleanones

Identifiers

PMID35744938
PMCPMC9230782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.