Evidence map›Paper›PMID 35744926›Full record

ArticleMolecules (Basel, Switzerland)2022

Development of a Novel Class of Pyridazinone Derivatives as Selective MAO-B Inhibitors.

Mehmet Abdullah Alagöz, Jong Min Oh, Yaren Nur Zenni, Zeynep Özdemir, Mohamed A Abdelgawad, Ibrahim A Naguib, Mohammed M Ghoneim, Nicola Gambacorta, Orazio Nicolotti, Hoon Kim and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Investigation on NovelMolecules (Basel, Switzerland) · 2023
    Article
  7. Synthesis, Characterization and Cytotoxic Evaluation of New Pyrrolo[1,2-International journal of molecular sciences · 2023
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mehmet Abdullah AlagözDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, 44280 Malatya, Turkey.ORCID 0000-0001-5190-7196
Jong Min OhDepartment of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Korea.
Yaren Nur ZenniDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, 44280 Malatya, Turkey.
Zeynep ÖzdemirDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, 44280 Malatya, Turkey.ORCID 0000-0003-4559-2305
Mohamed A AbdelgawadDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Al Jouf 72341, Saudi Arabia.ORCID 0000-0001-9035-5638
Ibrahim A NaguibDepartment of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.ORCID 0000-0002-5923-1466
Mohammed M GhoneimDepartment of Pharmacy Practice, Faculty of Pharmacy, AlMaarefa University, Ad Diriyah 13713, Saudi Arabia.ORCID 0000-0002-9179-4373
Nicola GambacortaDipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari "Aldo Moro", Via E. Orabona, 4, 70125 Bari, Italy.ORCID 0000-0003-1965-1519
Orazio NicolottiDipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari "Aldo Moro", Via E. Orabona, 4, 70125 Bari, Italy.ORCID 0000-0001-6533-5539
Hoon KimDepartment of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Korea.ORCID 0000-0002-7203-3712
Bijo MathewDepartment of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi 682 041, India.

Funding

Research Foundation of İnönü University TCD-2021-2558
6 · The paper itself

Abstract

Sixteen compounds (

Indexed as

Monoamine OxidaseMonoamine Oxidase InhibitorsDopamine AgentsKineticsMolecular Docking SimulationStructure-Activity RelationshipDopamine AgentsMonoamine OxidaseMonoamine Oxidase Inhibitorsdockingkineticsmonoamine oxidase-BPAMPApyridazinonesreversibility

Identifiers

PMID35744926
PMCPMC9230784

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.