Evidence map›Paper›PMID 35744840›Full record

ArticleMolecules (Basel, Switzerland)2022

Dihydrotanshinone I Enhances Cell Adhesion and Inhibits Cell Migration in Osteosarcoma U-2 OS Cells through CD44 and Chemokine Signaling.

Lanyan Fan, Chen Peng, Xiaoping Zhu, Yawen Liang, Tianyi Xu, Peng Xu, Shihua Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lanyan FanJoint Research Centre for Engineering Biology, Zhejiang University-University of Edinburgh Institute, Zhejiang University, Haining 314400, China.
Chen PengResearch Center of Siyuan Natural Pharmacy and Biotoxicology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-9449-7606
Xiaoping ZhuJoint Research Centre for Engineering Biology, Zhejiang University-University of Edinburgh Institute, Zhejiang University, Haining 314400, China.
Yawen LiangResearch Center of Siyuan Natural Pharmacy and Biotoxicology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Tianyi XuResearch Center of Siyuan Natural Pharmacy and Biotoxicology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Peng XuJoint Research Centre for Engineering Biology, Zhejiang University-University of Edinburgh Institute, Zhejiang University, Haining 314400, China.
Shihua WuJoint Research Centre for Engineering Biology, Zhejiang University-University of Edinburgh Institute, Zhejiang University, Haining 314400, China.ORCID 0000-0002-1669-7522
Zhejiang University-University of Edinburgh Institute · CNZhejiang University · CN

Funding

Fundamental Research Funds for the Central Universities 2021QNA6001 and 2021FZZX003-02-12)National Natural Science Foundation of China 21672188Natural Science Foundation of Zhejiang Province LY20B020011
6 · The paper itself

Abstract

In the screening of novel natural products against cancer using an in vitro cancer cell model, we recently found that tanshinones from a traditional Chinese medicine, the rhizome of

Indexed as

Bone NeoplasmsOsteosarcomaSalvia miltiorrhizaCell AdhesionCell MovementChemokinesFuransHumansHyaluronan ReceptorsPhenanthrenesPhosphatidylinositol 3-KinasesQuinonesCD44 protein, humanChemokinesdihydrotanshinone IFuransHyaluronan ReceptorsPhenanthrenesPhosphatidylinositol 3-KinasesQuinonesCD44cell adhesioncell migrationdihydrotanshinone IosteosarcomaSalvia miltiorrhiza Bunge (Danshen)

Identifiers

PMID35744840
PMCPMC9231138
OpenAlexW4282826620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.