Evidence map›Paper›PMID 35744828›Full record

ReviewMolecules (Basel, Switzerland)2022

Plant Antimicrobial Peptides (PAMPs): Features, Applications, Production, Expression, and Challenges.

Olalekan Olanrewaju Bakare, Arun Gokul, Adewale Oluwaseun Fadaka, Ruomou Wu, Lee-Ann Niekerk, Adele Mariska Barker, Marshall Keyster, Ashwil Klein

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Overexpression ofFrontiers in plant science · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Antifungal Action ofAntioxidants (Basel, Switzerland) · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Olalekan Olanrewaju BakareEnvironmental Biotechnology Laboratory, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-5856-8286
Arun GokulDepartment of Plant Sciences, Qwaqwa Campus, University of the Free State, Phuthadithjaba 9866, South Africa.ORCID 0000-0003-1575-0632
Adewale Oluwaseun FadakaDepartment of Science and Innovation/Mintek Nanotechnology Innovation Centre, Bio labels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-3952-2098
Ruomou WuEnvironmental Biotechnology Laboratory, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.
Lee-Ann NiekerkEnvironmental Biotechnology Laboratory, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-9788-3131
Adele Mariska BarkerEnvironmental Biotechnology Laboratory, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0003-1746-5421
Marshall KeysterEnvironmental Biotechnology Laboratory, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-8718-736X
Ashwil KleinPlant Omics Laboratory, Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.ORCID 0000-0002-5606-886X

Funding

Department of Science and Technology 120712
6 · The paper itself

Abstract

The quest for an extraordinary array of defense strategies is imperative to reduce the challenges of microbial attacks on plants and animals. Plant antimicrobial peptides (PAMPs) are a subset of antimicrobial peptides (AMPs). PAMPs elicit defense against microbial attacks and prevent drug resistance of pathogens given their wide spectrum activity, excellent structural stability, and diverse mechanism of action. This review aimed to identify the applications, features, production, expression, and challenges of PAMPs using its structure-activity relationship. The discovery techniques used to identify these peptides were also explored to provide insight into their significance in genomics, transcriptomics, proteomics, and their expression against disease-causing pathogens. This review creates awareness for PAMPs as potential therapeutic agents in the medical and pharmaceutical fields, such as the sensitive treatment of bacterial and fungal diseases and others and their utilization in preserving crops using available transgenic methods in the agronomical field. PAMPs are also safe to handle and are easy to recycle with the use of proteases to convert them into more potent antimicrobial agents for sustainable development.

Indexed as

Anti-Infective AgentsAntimicrobial Cationic PeptidesAnimalsAntimicrobial PeptidesCrops, AgriculturalPathogen-Associated Molecular Pattern MoleculesAnti-Infective AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesPathogen-Associated Molecular Pattern MoleculesbiotechnologydrugengineeringmodellingPAMPsstructure

Identifiers

PMID35744828
PMCPMC9229691

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.