ArticleMolecules (Basel, Switzerland)2022
Regiospecific Hydrogenation of Bromochalcone by Unconventional Yeast Strains.
Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Whole-Cell Biocatalysis for the Production of Structurally Diverse Methoxydihydrochalcones: Broad Activity of theMolecules (Basel, Switzerland) · 2026Article
- Effect of Sunlight-Induced Isomerisation on the Biotransformation of 4'-Hydroxychalcones byInternational journal of molecular sciences · 2025Article
- Efficient Production of 4'-Hydroxydihydrochalcones Using Non-Conventional Yeast Strains.International journal of molecular sciences · 2024Article
- Bioreduction of 4'-Hydroxychalcone in Deep Eutectic Solvents: Optimization and Efficacy with Various Yeast Strains.International journal of molecular sciences · 2024Article
- Multienzymatic biotransformation of flavokawain B by entomopathogenic filamentous fungi: structural modifications and pharmacological predictions.Microbial cell factories · 2024Article
- Biotransformation of Flavonoids with -NOInternational journal of molecular sciences · 2023Article
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Authors and funding
10 authors.
Funding
Abstract
This research aimed to select yeast strains capable of the biotransformation of selected 2'-hydroxybromochalcones. Small-scale biotransformations were carried out using four substrates obtained by chemical synthesis (2'-hydroxy-2″-bromochalcone, 2'-hydroxy-3″-bromochalcone, 2'-hydroxy-4″-bromochalcone and 2'-hydroxy-5'-bromochalcone) and eight strains of non-conventional yeasts. Screening allowed for the determination of the substrate specificity of selected microorganisms and the selection of biocatalysts that carried out the hydrogenation of tested compounds in the most effective way. It was found that the position of the bromine atom has a crucial influence on the degree of substrate conversion by the tested yeast strains. As a result of the biotransformation of the 2'-hydroxybromochalcones, the corresponding 2'-hydroxybromodihydrochalcones were obtained. The products obtained belong to the group of compounds with high potential as precursors of sweet substances.
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