Evidence map›Paper›PMID 35744731›Full record

ArticleMicroorganisms2022

Clinical Features and Outcome of Multidrug-Resistant Osteoarticular Tuberculosis: A 12-Year Case Series from France.

Isabelle Bonnet, Elie Haddad, Lorenzo Guglielmetti, Pascale Bémer, Louis Bernard, Anne Bourgoin, Rachel Brault, Gaud Catho, Eric Caumes, Lélia Escaut and 24 more

Abstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Isabelle BonnetCimi-Paris, INSERM, U1135, Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Université, 75013 Paris, France.
Elie HaddadService de Maladies Infectieuses et Tropicales, Hôpital Pitié-Salpêtrière, AP-HP, INSERM 1136, Sorbonne-Université, 75013 Paris, France.ORCID 0000-0002-0271-0888
Lorenzo GuglielmettiCimi-Paris, INSERM, U1135, Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Université, 75013 Paris, France.
Pascale BémerDepartment of Bacteriology, University Hospital, CHU Nantes, 44000 Nantes, France.ORCID 0000-0001-5892-2946
Louis BernardService de Médecine Interne et Maladies Infectieuses, Centre Hospitalier Régional Universitaire de Tours, 37000 Tours, France.
Anne BourgoinService de Virologie et Mycobactériologie, Centre Hospitalier Universitaire de Poitiers, 86000 Poitiers, France.
Rachel BraultService de Rhumatologie, Centre Hospitalier Universitaire de Poitiers, 86000 Poitiers, France.
Gaud CathoService de Maladies Infectieuses et Tropicales, Hospices Civils de Lyon, 69002 Lyon, France.
Eric CaumesService de Maladies Infectieuses et Tropicales, Hôpital Pitié-Salpêtrière, AP-HP, INSERM 1136, Sorbonne-Université, 75013 Paris, France.
Lélia EscautService de Maladies Infectieuses et Tropicales, Hôpital Bicêtre, AP-HP, Université Paris Saclay, 94270 Le Kremlin-Bicêtre, France.
Eric FourniolsService de Chirurgie Orthopédique, Hôpital Pitié-Salpêtrière, AP-HP, Sorbonne-Université, 75013 Paris, France.
Mathilde Fréchet-JachymSanatorium, Centre Hospitalier de Bligny, 91640 Briis-sous-Forges, France.
Alice GaudartService de Bactériologie, Centre Hospitalier Universitaire de Nice, 06000 Nice, France.
Hélène GuillotService de Médecine Interne, Hôpital Robert Ballanger, 93600 Aulnay-sous-Bois, France.
Barthélémy Lafon-DesmursService de Maladies Infectieuses et Tropicales, Centre Hospitalier de Tourcoing, 59200 Tourcoing, France.
Jean-Philippe LanoixService de Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire d'Amiens-Picardie, 80054 Amiens, France.
Philippe LanotteService de Bactériologie, Centre Hospitalier Universitaire de Tours, 37000 Tours, France.
Adrien LemaignenService de Médecine Interne et Maladies Infectieuses, Centre Hospitalier Régional Universitaire de Tours, 37000 Tours, France.ORCID 0000-0001-5974-5689
Bénédicte LemaireSanatorium, Centre Hospitalier de Bligny, 91640 Briis-sous-Forges, France.
Nadine LemaitreService de Bactériologie, Centre Hospitalier Universitaire d'Amiens-Picardie, 59200 Tourcoing, France.
Christophe MichauService de Maladies Infectieuses et Tropicales, Centre Hospitalier de Saint-Nazaire, 44606 Saint-Nazaire, France.
Philippe MorandService de Bactériologie, Hôpital Cochin, AP-HP, Centre-Université de Paris, 75014 Paris, France.
Faiza MougariService de Bactériologie, Hôpital Lariboisière, AP-HP, Nord-Université de Paris, 75018 Paris, France.
Dhiba Marigot-OuttandySanatorium, Centre Hospitalier de Bligny, 91640 Briis-sous-Forges, France.
Solène Patrat-DelonService de Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire de Rennes, 35033 Rennes, France.ORCID 0000-0001-6895-7894
Thomas PerpointService de Maladies Infectieuses et Tropicales, Hospices Civils de Lyon, 69002 Lyon, France.
Caroline PiauService de Bactériologie, Centre Hospitalier Universitaire de Rennes, 35033 Rennes, France.
Valérie PourcherService de Maladies Infectieuses et Tropicales, Hôpital Pitié-Salpêtrière, AP-HP, INSERM 1136, Sorbonne-Université, 75013 Paris, France.
Virginie ZarroukService de Médecine Interne, Hôpital Beaujon, AP-HP, Nord-Université de Paris, 92110 Clichy, France.
Valérie ZellerCentre de Référence des Infections Ostéo-Articulaires Complexes, Groupe Hospitalier Diaconesses Croix Saint-Simon, 75020 Paris, France.
Nicolas VezirisCimi-Paris, INSERM, U1135, Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Université, 75013 Paris, France.
Stéphane JauréguiberryService de Maladies Infectieuses et Tropicales, Hôpital Pitié-Salpêtrière, AP-HP, INSERM 1136, Sorbonne-Université, 75013 Paris, France.
Alexandra AubryCimi-Paris, INSERM, U1135, Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Université, 75013 Paris, France.ORCID 0000-0003-4230-4793
CRIOAC Pitié-Salpêtrière and the TB Consilium of the National Reference Center for Mycobacteria

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal treatment for osteoarticular infection due to multidrug-resistant tuberculosis strains (MDR-OATB) remains unclear. This study aims to evaluate the diagnosis, management and outcome of MDR-OATB in France. We present a case series of MDR-OATB patients reviewed at the French National Reference Center for Mycobacteria between 2007 and 2018. Medical history and clinical, microbiological, treatment and outcome data were collected. Twenty-three MDR-OATB cases were reported, representing 3% of all concurrent MDR-TB cases in France. Overall, 17 were male, and the median age was 32 years. Six patients were previously treated for TB, including four with first-line drugs. The most frequently affected site was the spine (

Indexed as

boneMDR-TBspinalXDR-TB

Identifiers

PMID35744731
PMCPMC9229793

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.