Evidence map›Paper›PMID 35744696›Full record

ArticleMicroorganisms2022

Targeting the Gut Microbiota and Host Immunity with a

David Shapiro, Fatemeh Ramezani Kapourchali, Anthony Santilli, Yingchun Han, Gail A M Cresci

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David ShapiroDepartment of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-8667-8861
Fatemeh Ramezani KapourchaliDepartment of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH 44195, USA.
Anthony SantilliDepartment of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0001-8381-7072
Yingchun HanDepartment of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH 44195, USA.
Gail A M CresciDepartment of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-5717-7099
Cleveland Clinic · US

Funding

Alcohol and intestinal microvascular endothelium-immune axis and the role of gut derived immune nutrientsR01AA028043 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI CRESCI, GAIL ANN · 2020 to 2024
$2.6M
NIAAA NIH HHS R01 AA028043NIH HHS R01AA028043- 01A1
6 · The paper itself

Abstract

Antibiotic therapy is necessary for the treatment of bacterial infections; however, it can also disrupt the balance and function of commensal gut microbes and negatively affect the host. Probiotics have been tested as a means to counteract the negative effects of antibiotic therapy, but many probiotics are also likely destroyed by antibiotics when taken together. Here we aimed to test the efficacy of a non-pathogenic spore-forming

Indexed as

antibioticsgut microbiomeintestinenutrition immunityprobioticretinoic acid

Identifiers

PMID35744696
PMCPMC9228267
OpenAlexW4282594632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.