ArticleMicroorganisms2022
Dietary Cysteamine Supplementation Remarkably Increased Feed Efficiency and Shifted Rumen Fermentation toward Glucogenic Propionate Production via Enrichment of
Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of flavonoids use into beef and dairy cattle diet: Performance, antioxidant status, ruminal fermentation, meat quality, and milk composition.Frontiers in veterinary science · 2023Pooled it
- Dietary supplementation of cysteamine promotes Hu lamb growth performance via somatotropic axis potentiation.Animal bioscience · 2026Article
- Dietary Puerarin Modulates the Rumen Microbiota and Enhances Growth Performance and Rumen Fermentation in Hu Sheep.Animals : an open access journal from MDPI · 2026Article
- Rumen-derived Prevotella and Megasphaera elsdenii mitigate methane production through functional modulation of rumen microbial metabolism.Journal of animal science and biotechnology · 2026Article
- Impact of Opuntia spp. by-product silage on sheep metabolic profile, rumen fermentation and microbial communities.BMC veterinary research · 2026Article
- Mineral-Vitamin Complexes in Sheep Nutrition: Patent Analysis and Functional Evaluation for Pregnant Ewes and Lambs.Molecules (Basel, Switzerland) · 2026Review
- Article
- Deciphering cysteamine's impact on cashmere-producing traits of cashmere goats: a transcriptomic and metabolomic perspective.Frontiers in veterinary science · 2026Article
- Distinct Rumen Microbial Features and Host Metabolic Responses in Three Cervid Species.Animals : an open access journal from MDPI · 2025Article
- Effects of Alkaline Mineral Complex Supplementation on Growth Performance, Meat Quality, Serum Biochemical Parameters, and Digestive Function of Fattening Lambs.Animals : an open access journal from MDPI · 2025Article
- Effects of varying levels of coated cysteamine hydrochloride in diet on growth performance and carcass quality of steers.Animal bioscience · 2025Article
- Effects ofAnimals : an open access journal from MDPI · 2025Article
- Effects of Creep Feeding from Birth to Suckling Period on Hanwoo Calves' Growth Performance and Microbiota.Animals : an open access journal from MDPI · 2025Article
- Effects of increasing levels of rubber seed cake on growth performance, nutrient digestion metabolism, serum biochemical parameters, and rumen microbiota of Hu sheep.BMC veterinary research · 2025Article
- Effect of adding citrus flavonoid (Bioflavex) to diet on growth, feed efficiency, rumen histomorphology, carcass traits and meat quality of lambs.Frontiers in veterinary science · 2025Article
- Rumen and hindgut microbiome regulate average daily gain of preweaning Holstein heifer calves in different ways.Microbiome · 2024Article
- Exploring the Effect of GastrointestinalAnimals : an open access journal from MDPI · 2024Review
- Colon impairments and inflammation driven by an altered gut microbiota leads to social behavior deficits rescued by hyaluronic acid and celecoxib.BMC medicine · 2024Article
- Coated cysteamine, a potential feed additive for ruminants - An updated review.Animal bioscience · 2024Article
- Exploring optimal folic acid supplementation levels for lactating-pregnant rabbit does with different litter size.Journal of animal science · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
Cysteamine (CS) is an essential nutritional regulator that improves the productive performance of animals by regulating somatotropic hormone secretion. To investigate the fattening potential and effects of CS on rumen microbial fermentation, 48 feedlot lambs were randomly assigned to four groups and fed diets supplemented with different CS concentrations (0, 20, 40, and 60 mg/kg BW). An increase in dietary CS concentrations linearly increased the average daily gain (ADG) and dry matter intake (p < 0.05) but decreased the feed-to-gain ratio (p < 0.01). For the serum hormone, increasing the dietary CS concentration linearly decreased somatostatin and leptin concentration (p < 0.01) but linearly increased the concentration of growth hormone and insulin-like growth factor 1 (p < 0.01). Regarding rumen fermentation, ruminal pH, ammonia-N, and butyrate content did not differ among the four treatments, although dietary CS supplementation linearly increased microbial protein and propionate and decreased the amount of acetate (p < 0.05). Furthermore, an increase in dietary CS concentrations quadratically decreased the estimated methane production and methane production per kg ADG (p < 0.05). High-throughput sequencing revealed that increased dietary CS concentrations quadratically increased Prevotella (p < 0.05), and Prevotella and norank_f__norank_o__Clostridia_UCG-014 were positively correlated with growth performance and rumen fermentation in a Spearman correlation analysis (r > 0.55, p < 0.05). Overall, a CS concentration higher than 20 mg/kg BW produced growth-promoting effects by inhibiting somatostatin concentrations and shifting the rumen toward glucogenic propionate fermentation by enriching Prevotella. In addition, Prevotella and norank_f__norank_o__Clostridia_UCG-014 were positively correlated with growth performance in lambs.
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