Evidence map›Paper›PMID 35744480›Full record

ArticleMicromachines2022

Sub-100 nm Nanoparticle Upconcentration in Flow by Dielectrophoretic Forces.

Maria Dimaki, Mark Holm Olsen, Noemi Rozlosnik, Winnie E Svendsen

Abstract read
In one paragraph

Article in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria DimakiDTU Bioengineering, Technical University of Denmark, Søltofts Plads, Bldg 221, 2800 Kongens Lyngby, Denmark.ORCID 0000-0001-5037-2388
Mark Holm OlsenCenter for Plastics and Packaging Technology, Teknologisk Institut, Gregersensvej 1, 2630 Taastrup, Denmark.
Noemi RozlosnikEir Diagnostics ApS, Muslingevej 36B, 8250 Egå, Denmark.
Winnie E SvendsenDTU Bioengineering, Technical University of Denmark, Søltofts Plads, Bldg 221, 2800 Kongens Lyngby, Denmark.ORCID 0000-0002-9197-6505

Funding

European Union 604069
6 · The paper itself

Abstract

This paper presents a novel microfluidic chip for upconcentration of sub-100 nm nanoparticles in a flow using electrical forces generated by a DC or AC field. Two electrode designs were optimized using COMSOL Multiphysics and tested using particles with sizes as low as 47 nm. We show how inclined electrodes with a zig-zag three-tooth configuration in a channel of 20 µm width are the ones generating the highest gradient and therefore the largest force. The design, based on AC dielectrophoresis, was shown to upconcentrate sub-100 nm particles by a factor of 11 using a flow rate of 2-25 µL/h. We present theoretical and experimental results and discuss how the chip design can easily be massively parallelized in order to increase throughput by a factor of at least 1250.

Indexed as

dielectrophoresismicrofluidicsnanoparticlesupconcentration

Identifiers

PMID35744480
PMCPMC9230564

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.