Evidence map›Paper›PMID 35744339›Full record

ArticleMaterials (Basel, Switzerland)2022

3D Printing of PLLA/Biomineral Composite Bone Tissue Engineering Scaffolds.

Fangli Gang, Weilong Ye, Chunyang Ma, Wenting Wang, Yi Xiao, Chang Liu, Xiaodan Sun

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Fangli GangDepartment of Biology, Xinzhou Teachers University, Xinzhou 034000, China.ORCID 0000-0002-1507-2539
Weilong YeBeijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Beijing Stomatological Hospital, School of Stomatology, Capital Medical University, Beijing 100050, China.ORCID 0000-0003-3939-752X
Chunyang MaKey Laboratory of Biomechanics and Mechanobiology, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.
Wenting WangDepartment of Biology, Xinzhou Teachers University, Xinzhou 034000, China.
Yi XiaoDepartment of Biology, Xinzhou Teachers University, Xinzhou 034000, China.
Chang LiuDepartment of Stomatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Xiaodan SunKey Laboratory of Advanced Materials of Ministry of Education, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China.
Xinzhou Teachers University · CNCapital Medical University · CNBeihang University · CNTsinghua University · CN

Funding

Fund of Key Laboratory of Advanced Materials of Ministry of Education ADV21-16Scientific and Technologial Innovation Programs of Higher Education Institutions in Shanxi 2021L461Shanxi Applied Basic Research Project 20210302124286
6 · The paper itself

Abstract

Tissue engineering is one of the most effective ways to treat bone defects in recent years. However, current highly active bone tissue engineering (BTE) scaffolds are mainly based on the addition of active biological components (such as growth factors) to promote bone repair. High cost, easy inactivation and complex regulatory requirements greatly limit their practical applications. In addition, conventional fabrication methods make it difficult to meet the needs of personalized customization for the macroscopic and internal structure of tissue engineering scaffolds. Herein, this paper proposes to select five natural biominerals (eggshell, pearl, turtle shell, degelatinated deer antler and cuttlebone) with widely available sources, low price and potential osteo-inductive activity as functional particles. Subsequently compounding them into L-polylactic acid (PLLA) biomaterial ink to further explore 3D printing processes of the composite scaffold, and reveal their potential as biomimetic 3D scaffolds for bone tissue repair. The research results of this project provide a new idea for the construction of a 3D scaffold with growth-factor-free biomimetic structure, personalized customization ability and osteo-inductive activity.

Indexed as

3D printingbiomineralsbone tissue engineering

Identifiers

PMID35744339
PMCPMC9228366
OpenAlexW4283034420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.