Evidence map›Paper›PMID 35744100›Full record

ArticleMaterials (Basel, Switzerland)2022

Effect of Dentin Desensitizer Containing Novel Bioactive Glass on the Permeability of Dentin.

Ji-Hyun Jang, Hyun-Jung Kim, Joo-Young Choi, Hae-Won Kim, Samjin Choi, Soogeun Kim, Ayoung Bang, Duck-Su Kim

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ji-Hyun JangDepartment of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul 02453, Korea.ORCID 0000-0002-4672-3381
Hyun-Jung KimDepartment of Conservative Dentistry, Kyung Hee University Dental Hospital, Seoul 02453, Korea.ORCID 0000-0002-7674-9363
Joo-Young ChoiDepartment of Conservative Dentistry, Graduate School, Kyung Hee University, Seoul 02453, Korea.
Hae-Won KimInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan 31116, Korea.
Samjin ChoiDepartment of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul 02453, Korea.ORCID 0000-0003-3498-0652
Soogeun KimDepartment of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul 02453, Korea.ORCID 0000-0001-5483-6661
Ayoung BangDepartment of Biomedical Engineering, College of Medicine, Kyung Hee University, Seoul 02453, Korea.
Duck-Su KimDepartment of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul 02453, Korea.ORCID 0000-0001-9386-6062
Kyung Hee University · KRKyung Hee University Dental Hospital · KR

Funding

National Research Foundation of Korea 2019R1F1A1057615National Research Foundation of Korea 2021R1A5A2022318National Research Foundation of Korea 2021R1F1A1045987
6 · The paper itself

Abstract

The objective of this study was to evaluate the effect of novel bioactive glass (BAG)-containing desensitizers on the permeability of dentin. Experimental dentin desensitizers containing 3 wt% BAG with or without acidic functional monomers (10-MDP or 4-META) were prepared. A commercial desensitizer, Seal & Protect (SNP), was used as a control. To evaluate the permeability of dentin, real-time dentinal fluid flow (DFF) rates were measured at four different time points (demineralized, immediately after desensitizer application, after two weeks in simulated body fluid (SBF), and post-ultrasonication). The DFF reduction rate (ΔDFF) was also calculated. The surface changes were analyzed using field emission scanning electron microscopy (FE-SEM). Raman spectroscopy was performed to analyze chemical changes on the dentin surface. The ΔDFF of the desensitizers containing BAG, BAG with 10-MDP, and BAG with 4-META significantly increased after two weeks of SBF storage and post-ultrasonication compared to the SNP at each time point (p < 0.05). Multiple precipitates were observed on the surfaces of the three BAG-containing desensitizers. Raman spectroscopy revealed hydroxyapatite (HAp) peaks on the dentin surfaces treated with the three BAG-containing desensitizers. Novel BAG-containing dentin desensitizers can reduce the DFF rate about 70.84 to 77.09% in the aspect of reduction of DFF through the HAp precipitations after two weeks of SBF storage.

Indexed as

bioactive glassdentin desensitizerdentin hypersensitivityRaman spectroscopyreal-time dentinal fluid flow

Identifiers

PMID35744100
PMCPMC9227448
OpenAlexW4282034087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.