ReviewMedicina (Kaunas, Lithuania)2022
Intra-Abdominal Hypertension: A Systemic Complication of Severe Acute Pancreatitis.
Review in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06672601 (The HYPA Study), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The HYPA Study: Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients Undergoing Open and Robotic Pancreatic Procedures
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Neostigmine for non-mild acute pancreatitis: A systematic review and meta-analysis of randomized controlled trials.Frontiers in pharmacology · 2023Pooled it
- Individualized Lung-Protective Ventilation Strategy Based on Esophageal Pressure Monitoring in Patients With ARDS Associated With Severe Acute Pancreatitis-A Randomized Controlled Trial.World journal of surgery · 2025Trial
- Continuous monitoring of intra-abdominal pressure: cumulative pressure exposure predicts early acute kidney injury in animal model.World journal of emergency surgery : WJES · 2026Article
- Impact of 24-hour urine output trajectories on intra-abdominal hypertension risk in acute pancreatitis patients: Insights from MIMIC-IV database.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026Article
- Development of a nomogram prediction model for postoperative intra-abdominal hypertension in patients with intra-abdominal infection sepsis based on analgesic drug selection.Frontiers in surgery · 2026Article
- Application of electrical impedance tomography-guided PEEP titration in acute respiratory distress syndrome patients with intra-abdominal hypertension.World journal of emergency medicine · 2026Article
- Article
- Contrast-enhanced CT-based prediction models for early intervention efficacy and in-hospital mortality risk in acute necrotizing pancreatitis with persistent organ failure.European radiology · 2025Article
- Anticoagulation therapy for intra-abdominal hypertension in patients with acute pancreatitis.BMC gastroenterology · 2025Article
- Observational
- Cumulative intra-abdominal pressure exposure and dynamic trajectories in ICU-admitted patients reveal prognostic determinants of severe acute pancreatitis.World journal of emergency surgery : WJES · 2025Article
- Relationship between intra-bladder pressure and acute kidney injury in patients with acute pancreatitis: interpretable machine learning approach.BMC nephrology · 2025Article
- Influencing factor analysis and clinical efficacy of early intervention in severe acute pancreatitis with persistent organ failure.Scientific reports · 2025Observational
- Diagnostic and therapeutic management of severe acute pancreatitis. Evidence based medicine (EBM) clinical practice guidelines.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Article
- Development of a nomogram for predicting the intraperitoneal rupture of necrotic collection in patients with necrotizing pancreatitis.Frontiers in medicine · 2025Article
- Article
- The relationship between inflammatory cytokines and in-hospital complications of acute pancreatitis.Immunity, inflammation and disease · 2024Article
- Severe Acute Pancreatitis Treated with Negative Pressure Wound Therapy System: Influence of Laboratory Markers.Journal of clinical medicine · 2023Article
- Evaluation of Intra-Abdominal Hypertension Parameters in Patients with Acute Pancreatitis.Life (Basel, Switzerland) · 2023Article
- Neostigmine for the treatment of acute pancreatitis: a protocol for a systematic review and meta-analysis.BMJ open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with severe acute pancreatitis (SAP) present complications and organ failure, which require treatment in critical care units. These extrapancreatic complications determine the clinical outcome of the disease. Intra-abdominal hypertension (IAH) deteriorates the prognosis of SAP. In this paper, relevant recent literature was reviewed, as well as the authors' own experiences, concerning the clinical importance of IAH and its treatment in SAP. The principal observations confirmed that IAH is a frequent consequence of SAP but is practically absent in mild disease. Common manifestations of AP such as pain, abdominal distension, and paralytic ileus contribute to increased abdominal pressure, as well as fluid loss in third space and aggressive fluid replacement therapy. A severe increase in IAP can evolve to abdominal compartment syndrome and new onset organ failure. Conservative measures are useful, but invasive interventions are necessary in several cases. Percutaneous drainage of major collections is preferred when possible, but open decompressive laparotomy is the final possibility in some cases in order to definitively reduce abdominal pressure. Intra-abdominal pressure should be measured in all SAP cases that worsen despite adequate treatment in critical care units. Conservative measures must be introduced to treat IAH, including negative fluid balance, digestive decompression by gastric-rectal tube, and prokinetics, including neostigmine. In the case of insufficient responses to these measures, minimally invasive interventions should be preferred.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.