Evidence map›Paper›PMID 35743928›Full record

ArticleLife (Basel, Switzerland)2022

In Vitro Characterization of the Human Skeletal Stem Cell-like Properties of Primary Bone-Derived Mesenchymal Stem/Stromal Cells in Patients with Late and Early Hip Osteoarthritis.

Lara Jasenc, Klemen Stražar, Anže Mihelič, Rene Mihalič, Rihard Trebše, Gregor Haring, Matjaž Jeras, Janja Zupan

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lara JasencDepartment of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, Askerceva 7, 1000 Ljubljana, Slovenia.
Klemen StražarDepartment of Orthopaedic Surgery, University Medical Centre Ljubljana, Zaloska 9, 1000 Ljubljana, Slovenia.
Anže MiheličValdoltra Orthopaedic Hospital, Jadranska 31, 6280 Ankaran, Slovenia.
Rene MihaličValdoltra Orthopaedic Hospital, Jadranska 31, 6280 Ankaran, Slovenia.ORCID 0000-0003-2649-5913
Rihard TrebšeFaculty of Medicine, University of Ljubljana Vrazov trg 2, 1000 Ljubljana, Slovenia.ORCID 0000-0002-1075-3351
Gregor HaringInstitute of Forensic Medicine, Faculty of Medicine, University of Ljubljana., Korytkova 2, 1000 Ljubljana, Slovenia.
Matjaž JerasDepartment of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, Askerceva 7, 1000 Ljubljana, Slovenia.
Janja ZupanDepartment of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, Askerceva 7, 1000 Ljubljana, Slovenia.ORCID 0000-0002-0211-8470
University of Ljubljana · SIOrthopaedic Hospital Valdoltra · SI

Funding

Ljubljana University Medical Centre Mesenchymal stem cells in hip synoviumSlovenian Research Agency J3-1749Slovenian Research Agency P1-0420 (A)
6 · The paper itself

Abstract

Human skeletal stem cells (hSSCs) were recently identified as podoplanin (PDPN)/CD73/CD164-positive and CD146-negative cells that decline with age, and play a role in the pathogenesis of osteoarthritis (OA). The aim of this study was to identify the hSSC-like properties of bone-derived mesenchymal stem/stromal cells (MSCs) of patients with late and early OA.

Indexed as

bone-derived mesenchymal stem/stromal cells (MSCs)CD146CD164CD73early OAhuman skeletal stem cells (hSSCs)immunophenotypinglate osteoarthritis (OA)podoplanin (PDPN)trilineage differentiation

Identifiers

PMID35743928
PMCPMC9228448
OpenAlexW4283020812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.