Evidence map›Paper›PMID 35743767›Full record

ArticleJournal of personalized medicine2022

Number of Teeth and Nutritional Status Parameters Are Related to Intima-Media Thickness in Dalmatian Kidney Transplant Recipients.

Maja Dodig Novaković, Sanja Lovrić Kojundžić, Mislav Radić, Marijana Vučković, Andrea Gelemanović, Marija Roguljić, Katja Kovačević, Josip Orešković, Josipa Radić

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Maja Dodig NovakovićDepartment of Radiology, General Hospital Šibenik, 22000 Šibenik, Croatia.
Sanja Lovrić KojundžićDepartment of Diagnostic and Interventional Radiology, University Hospital of Split, 21000 Split, Croatia.ORCID 0000-0002-9975-2100
Mislav RadićDepartment of Internal Medicine, Division of Clinical Immunology and Rheumatology, University Hospital of Split, 21000 Split, Croatia.ORCID 0000-0003-0350-6800
Marijana VučkovićDepartment of Nephrology and Dialysis, University Hospital of Split, 21000 Split, Croatia.
Andrea GelemanovićBiology of Robusteness Group, Mediterranean Institute for Life Sciences (MedILS), 21000 Split, Croatia.ORCID 0000-0001-9195-646X
Marija RoguljićDepartment of Oral Medicine and Periodontology, School of Medicine, Study of Dental Medicine, University of Split, 21000 Split, Croatia.
Katja KovačevićPrivate Dental Practice Split, 21000 Split, Croatia.
Josip OreškovićPrivate Dental Practice Josip Orešković, 34000 Požega, Croatia.
Josipa RadićDepartment of Internal Medicine, School of Medicine, University of Split, 21000 Split, Croatia.ORCID 0000-0003-2645-7597
University of Split · HRMediterranean Institute for Life Sciences · HRŠibenik University of Applied Sciences · HR

Funding

"Digitalization and improvement of nutritional care for 423 patients with chronic diseases" co-financed by the European Regional Development Fund through 424 the Operational Program "Competitiveness and Cohesion 2014-2020" KK.01.1.1.04.0115.
6 · The paper itself

Abstract

Although kidney transplantation significantly improves the quality of life of patients with end-stage renal disease (ESRD), the prevalence of cardiovascular disease (CVD) in kidney transplant recipients (KTRs) remains high. Atherosclerosis, post-transplantation metabolic changes, immunosuppressive therapy, and periodontitis contribute to elevated cardiovascular risk in this population. The aim of the study was to evaluate carotid intima-media thickness (IMT) as a surrogate marker of atherosclerosis and to analyze the possible risk factors for IMT in Dalmatian KTRs. Ninety-three KTRs were included in this study. Data on clinical and laboratory parameters, body composition, anthropometry, advanced glycation end-product (AGE) measurements, blood pressure, and arterial stiffness were collected. All participants underwent ultrasound examination of IMT and evaluation of periodontal status. KTRs with carotid IMT ≥ 0.9 were significantly older, had a lower level of total cholesterol, fat mass, end-diastolic velocity (EDV), and had fewer teeth. They also had significantly higher values of pulse wave velocity (PWV) and resistive index (RI). We found positive correlations between carotid IMT and duration of dialysis, age, PWV, AGE, RI, and average total clinical attachment level (CAL). The regression model showed that IMT in KTRs is associated with higher PWV, lower fat mass, and fewer teeth. The results of our study suggest that nutritional and periodontal status are associated with carotid IMT in KTRs.

Indexed as

advanced glycation end-productsatherosclerosisbody compositionkidney transplantnutritional statusperiodontitis

Identifiers

PMID35743767
PMCPMC9225251
OpenAlexW4283030377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.