Evidence map›Paper›PMID 35743765›Full record

ArticleJournal of personalized medicine2022

Impaired Human Sexual and Erectile Function Affecting Semen Quality, in Obstructive Sleep Apnea: A Pilot Study.

Konstantina Kyrkou, Emmanouil Alevrakis, Katerina Baou, Manos Alchanatis, Cornelia Poulopoulou, Christos Kanopoulos, Emmanouil Vagiakis, Dimitris Dikeos

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Konstantina KyrkouDepartment of Psychiatry, General Panarkadian Hospital of Tripoli "Evangelistria", 22100 Tripoli, Greece.
Emmanouil AlevrakisFourth Department of Respiratory Medicine, Sotiria Hospital of Chest Diseases, Mesogeion 152, 11527 Athens, Greece.ORCID 0000-0003-2699-1829
Katerina BaouFourth Department of Respiratory Medicine, Sotiria Hospital of Chest Diseases, Mesogeion 152, 11527 Athens, Greece.
Manos AlchanatisFirst Department of Respiratory Medicine, National and Kapodistrian University of Athens Medical School, 11527 Athens, Greece.
Cornelia PoulopoulouFirst Department of Neurology, National and Kapodistrian University of Athens Medical School, Eginition Hospital, 11528 Athens, Greece.ORCID 0000-0003-4581-6276
Christos KanopoulosBiopathological Diagnostic Research Laboratory "Analysi", Vas. Sofias 74 St., 11528 Athens, Greece.
Emmanouil VagiakisCritical Care and Pulmonary Services, Sleep Disorders Center, National and Kapodistrian University of Athens Medical School, Evangelismos Hospital, 10676 Athens, Greece.
Dimitris DikeosFirst Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, 11528 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is a rising problem, with important implications for public health. Recent evidence has revealed a link between OSA and reduced male fertility. We investigated the association between OSA and sexual and erectile function, as well as semen quality, and the effect of treatment by continuous positive airway pressure (CPAP). A total of 41 male subjects, who underwent polysomnography for suspected OSA, participated in the study. Erectile and sexual function were assessed with the 15-item International Index of Erectile Function (IIEF-15) questionnaire, blood samples, and sperm analysis. OSA patients after the initiation of CPAP treatment were followed for a period of 1 year. Thirty-two patients were diagnosed with OSA, and nine subjects without OSA were used as a control group. OSA patients demonstrated significantly impaired erectile function, reduced testosterone levels, and lower semen quality. Multivariable regression analysis showed that BMI and IIEF score were independent determinants of AHI. Sexual function improved after a year of CPAP therapy in OSA patients. This study provides further evidence regarding the association between OSA and erectile function impairment, as well as semen quality. Longitudinal adherence to CPAP treatment has a beneficial effect on erectile function.

Indexed as

erectile dysfunctionfertilitymale infertilityobstructive sleep apneapolysomnographysleep disorders

Identifiers

PMID35743765
PMCPMC9225560

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.