ArticleJournal of clinical medicine2022
The Analysis of Arterial Stiffness in Heart Failure Patients: The Prognostic Role of Pulse Wave Velocity, Augmentation Index and Stiffness Index.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- The association between pulse wave velocity and heart failure: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Impact of vascular and cardiac parameters on quality of life in patients undergoing catheter ablation for atrial fibrillation.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Precision Medicine in Heart Failure: Integrating Ventricular-Vascular Interaction and Arterial Stiffness into Patient Phenotyping.Journal of clinical medicine · 2026Review
- Evaluation of aortic stiffness with an oscillometric arteriograph device in patients with hypertension and ascending aortic aneurysm.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Empagliflozin and Arterial Stiffness in Patients with Type 2 Diabetes: A Real-World Case-Control StudyEndocrine, metabolic & immune disorders drug targets · 2026Article
- Article
- Predicting Early Atrial Fibrillation Recurrence Post-Electrical Cardioversion: A Critical Look at Bilateral Atrial Function.Journal of clinical medicine · 2025Article
- Exploring the Relationship Between Ejection Fraction, Arterial Stiffness, NT-proBNP, and Hospitalization Risk in Heart Failure Patients.Diagnostics (Basel, Switzerland) · 2024Article
- Article
- Arterial Stiffness and Heart Failure With Preserved Ejection Fraction.Journal of Korean medical science · 2024Review
- Inhaled nitric oxide testing in predicting prognosis in pulmonary hypertension due to left-sided heart diseases.ESC heart failure · 2023Article
- An Update on the Role of Arterial Stiffness in Heart Failure and the Treatment of Dyslipidemia.Journal of clinical medicine · 2023Article
- Acute and Chronic Effect of Physiological Factors on Arterial Stiffness.Journal of clinical medicine · 2023Article
- Aortic flow is abnormal in HFpEF.Wellcome open research · 2023Article
- Arterial Stiffness-What Do We Know about It and What Do We Expect from This Biomarker?Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The role of arterial stiffness in the pathogenesis and clinical outcome of heart failure (HF) patients has to be clarified. The aim of this study was to evaluate the prognostic role of arterial stiffness in HF patients discharged after acute episode of decompensation by evaluating cut-off values for clinical assessment. Methods: Patients admitted for decompensated heart failure (ADHF) underwent pre-discharge evaluation. Arterial stiffness was measured by aortic pulse wave velocity (aPWV), augmentation index (AIx75) and stiffness index (β0). Patients were also evaluated after discharge for a variable follow-up time. Results: We observed 199 patients (male 61.3%, age 76.2 ± 10.7 years) after discharge for a median of 437 days (IQR 247-903), 69 (34.7%) patients suffered HF with preserved ejection fraction (HFpEF), 45 (22.6%) patients experienced HF with mid-range ejection fraction (HFmEF) and 85 (42.7%) reported an HF with reduced ejection fraction (HFrEF). After the adjustment for principal confounders, aPWV, AIx75 and β0 were inversely correlated with free-event survival (p = 0.006, p < 0.001, p = 0.001): only β0 was inversely correlated with overall survival (p = 0.03). Analysing the threshold, overall survival was inversely correlated with β0 ≥3 (HR 2.1, p = 0.04) and free-event survival was inversely correlated with aPWV ≥10 m/s (HR 1.7, p = 0.03), AIx75 ≥ 25 (HR 2.4, p < 0.001), and β0 ≥ 3 (HR 2.0, p = 0.009). Dividing HF patients for LV ejection fraction, β0 and AIx75 appeared to be accurate prognostic predictors among the three different classes according to free-event survival. Conclusions: The non-invasive measurements of arterial stiffness proved to be strong prognostic parameters in HF patients discharged after an acute HF decompensation.
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