Evidence map›Paper›PMID 35743513›Full record

ArticleJournal of clinical medicine2022

Short- and Long-Term Effectiveness of Low-Level Laser Therapy Combined with Strength Training in Knee Osteoarthritis: A Randomized Placebo-Controlled Trial.

Martin Bjørn Stausholm, Ingvill Fjell Naterstad, Patricia Pereira Alfredo, Christian Couppé, Kjartan Vibe Fersum, Ernesto Cesar Pinto Leal-Junior, Rodrigo Álvaro Brandão Lopes-Martins, Jon Joensen, Jan Magnus Bjordal

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Martin Bjørn StausholmDepartment of Global Public Health and Primary Care, University of Bergen, 5009 Bergen, Norway.ORCID 0000-0001-9869-0705
Ingvill Fjell NaterstadDepartment of Global Public Health and Primary Care, University of Bergen, 5009 Bergen, Norway.ORCID 0000-0002-3619-4578
Patricia Pereira AlfredoDepartment of Physiotherapy, Occupational Therapy and Speech Therapy, School of Medicine, University of Sao Paulo, São Paulo 05508-070, Brazil.
Christian CouppéPhysical and Occupational Therapy Research Unit, Bispebjerg and Frederiksberg University Hospital, 2400 Copenhagen, Denmark.ORCID 0000-0003-1648-5746
Kjartan Vibe FersumDepartment of Global Public Health and Primary Care, University of Bergen, 5009 Bergen, Norway.
Ernesto Cesar Pinto Leal-JuniorDepartment of Global Public Health and Primary Care, University of Bergen, 5009 Bergen, Norway.
Rodrigo Álvaro Brandão Lopes-MartinsResearch Group of Biophotonics and Experimental Therapeutics in Health and Esthetics-Post Graduate Program in Human Movement and Rehabilitation, University Center of Anápolis, Anápolis 75083-515, Brazil.
Jon JoensenDepartment of Global Public Health and Primary Care, University of Bergen, 5009 Bergen, Norway.
Jan Magnus BjordalDepartment of Global Public Health and Primary Care, University of Bergen, 5009 Bergen, Norway.
University of Bergen · NOFrederiksberg Hospital · DKUniversidade de São Paulo · BRUniversidade Evangelica de Goiás · BRUniversidade Nove de Julho · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth physical activity and low-level laser therapy (LLLT) can reduce knee osteoarthritis (KOA) inflammation. We conducted a randomized clinical trial to investigate the short- and long-term effectiveness of LLLT combined with strength training in persons with KOA.

methodsFifty participants were randomly divided in two groups, one with LLLT plus strength training (

resultsThere were no significant between-group differences in the primary outcomes. However, in the laser group there was a significantly reduced number of participants using analgesic and non-steroidal anti-inflammatory drugs and increased performance in the sit-to-stand test versus placebo-control at week 52. The joint line pain pressure threshold (PPT) improved more in the placebo group than in the laser group, but only significantly at week 8. No other significant treatment effects were present. However, pain on movement and joint line PPT were worse in the placebo group at baseline, and therefore, it had more room for improvement. The short-term percentage of improvement in the placebo group was much higher than in similar trials.

conclusionsPain was reduced substantially in both groups. LLLT seemed to provide a positive add-on effect in the follow-up period in terms of reduced pain medication usage and increased performance in the sit-to-stand test.

Indexed as

inflammationknee osteoarthritislow-level laser therapy (LLLT)strength training

Identifiers

PMID35743513
PMCPMC9225274
OpenAlexW4283014346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.