Evidence map›Paper›PMID 35743504›Full record

ArticleJournal of clinical medicine2022

Real-World Clinical Outcomes and Replacement Factor VIII Consumption in Patients with Haemophilia A in Italy: A Comparison between Prophylaxis Pre and Post Octocog Alfa (BAY 81-8973).

Paolo Angelo Cortesi, Giovanni Di Minno, Ezio Zanon, Gaetano Giuffrida, Rita Carlotta Santoro, Renato Marino, Lucia Sara D'Angiolella, Ippazio Cosimo Antonazzo, Ginevra Squassabia, Francesco Clemente and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Personalized Prophylaxis with myPKFiTMedicina (Kaunas, Lithuania) · 2023
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Paolo Angelo CortesiResearch Centre on Public Health (CESP), University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0001-5241-4473
Giovanni Di MinnoRegional Reference Center for Coagulation Disorders, Federico II University Hospital, 80131 Naples, Italy.
Ezio ZanonHemophilia Center, University Hospital of Padua, 35128 Padua, Italy.ORCID 0000-0001-6149-1155
Gaetano GiuffridaDivision of Haematology, A.O.U. Policlinico Vittorio Emanuele, 95123 Catania, Italy.
Rita Carlotta SantoroCentre for Haemorrhagic and Thrombotic Disorders, "Pugliese Ciaccio" Hospital, 88100 Catanzaro, Italy.ORCID 0000-0002-5081-8201
Renato MarinoHaemophilia and Thrombosis Center, Giovanni XXIII Hospital of Bari, 70126 Bari, Italy.
Lucia Sara D'AngiolellaResearch Centre on Public Health (CESP), University of Milano-Bicocca, 20900 Monza, Italy.
Ippazio Cosimo AntonazzoResearch Centre on Public Health (CESP), University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0001-8046-4574
Ginevra SquassabiaResearch Centre on Public Health (CESP), University of Milano-Bicocca, 20900 Monza, Italy.
Francesco ClementeResearch Centre on Public Health (CESP), University of Milano-Bicocca, 20900 Monza, Italy.
Danilo Di LauraResearch Centre on Public Health (CESP), University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0001-5204-5364
Ernesto CiminoRegional Reference Center for Coagulation Disorders, Federico II University Hospital, 80131 Naples, Italy.
Samantha PascaHemophilia Center, University Hospital of Padua, 35128 Padua, Italy.ORCID 0000-0002-0954-013X
Daniela NicolosiDivision of Haematology, A.O.U. Policlinico Vittorio Emanuele, 95123 Catania, Italy.
Lorenzo Giovanni MantovaniResearch Centre on Public Health (CESP), University of Milano-Bicocca, 20900 Monza, Italy.
University of Milano-Bicocca · ITAzienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele · ITFederico II University Hospital · ITMultiMedica · ITAzienda Ospedaliera Pugliese Ciaccio · ITOspedale Pediatrico Giovanni XXIII · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: new generations of rFVIII products offered the possibility to improve personalized therapeutic approaches, reducing the number of infusions or increasing the protection against bleeding risk. The aim of this study was to assess the effectiveness of prophylaxis with BAY 81-8973 (octocog alfa, Kovaltry

Indexed as

cost-effectivenesshaemophilia Ainfusion frequencytreatment burden

Identifiers

PMID35743504
PMCPMC9224869
OpenAlexW4283020027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.