Evidence map›Paper›PMID 35743379›Full record

ArticleJournal of clinical medicine2022

Mechanical Fatigue Performance of Patient-Specific Polymer Plates in Oncologic Mandible Reconstruction.

Julian Lommen, Lara Schorn, Christoph Sproll, Norbert R Kübler, Luis Fernando Nicolini, Ricarda Merfort, Ayimire Dilimulati, Frank Hildebrand, Majeed Rana, Johannes Greven

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Julian LommenDepartment of Oral-, Maxillofacial and Facial Plastic Surgery, University Hospital Düsseldorf, Moorenstr. 5, 40225 Dusseldorf, Germany.ORCID 0000-0002-8470-6478
Lara SchornDepartment of Oral-, Maxillofacial and Facial Plastic Surgery, University Hospital Düsseldorf, Moorenstr. 5, 40225 Dusseldorf, Germany.ORCID 0000-0002-4301-0693
Christoph SprollDepartment of Oral-, Maxillofacial and Facial Plastic Surgery, University Hospital Düsseldorf, Moorenstr. 5, 40225 Dusseldorf, Germany.
Norbert R KüblerDepartment of Oral-, Maxillofacial and Facial Plastic Surgery, University Hospital Düsseldorf, Moorenstr. 5, 40225 Dusseldorf, Germany.
Luis Fernando NicoliniDepartment of Orthopedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, Pauwelsstreet 30, 52074 Aachen, Germany.
Ricarda MerfortDepartment of Orthopedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, Pauwelsstreet 30, 52074 Aachen, Germany.
Ayimire DilimulatiDepartment of Orthopedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, Pauwelsstreet 30, 52074 Aachen, Germany.
Frank HildebrandDepartment of Orthopedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, Pauwelsstreet 30, 52074 Aachen, Germany.
Majeed RanaDepartment of Oral-, Maxillofacial and Facial Plastic Surgery, University Hospital Düsseldorf, Moorenstr. 5, 40225 Dusseldorf, Germany.
Johannes GrevenDepartment of Orthopedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, Pauwelsstreet 30, 52074 Aachen, Germany.
Düsseldorf University Hospital · DERWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mandible defects are conventionally reconstructed using titanium plates. However, titanium causes metallic artifacts which impair radiological imaging. This study aims at evaluating mechanical fatigue of radiolucent fiber-reinforced polyetheretherketone (f-PEEK), polyetheretherketone (PEEK), polyetherketoneketone (PEKK), and polyphenylsulfone (PPSU) polymer plates for mandible reconstruction. A total of 30 plates (titanium [n = 6], f-PEEK [n = 6], PEEK [n = 6], PEKK [n = 6], PPSU [n = 6]) were implanted in synthetic mandibulectomized polyurethane mandibles. Servo-pneumatic mechanical testing with cyclic application of 30−300 N at 3 Hz was conducted. Bite forces were 70% on the unresected and 30% on the resected side. Total number of cycles was set to 250,000. Testing was aborted in case of plate or screw failure. Axial load to failure was tested with a speed of 1 mm/s. Kruskal−Wallis and Dunn’s post hoc tests were used. Titanium, f-PEEK, and PEEK showed no failure in fatigue testing and PPSU (p < 0.001) failed against titanium, f-PEEK, PEEK, and PEKK. Titanium allowed the highest load to failure compared to f-PEEK (p = 0.049), PEEK (p = 0.008), PEKK (p < 0.001), and PPSU (p = 0.007). f-PEEK, PEEK, and PEKK withstood expected physiological bite force. Although titanium plates provided the highest fatigue strength, f-PEEK and PEEK plates showed no failure over 250,000 chewing cycles indicating sufficient mechanical strength for mandible reconstruction.

Indexed as

computer-aided design (CAD)computer-aided manufacturing (CAM)mechanical propertiespolyetheretherketonepolyetherketoneketonepolymer platepolyphenylsulfonereconstruction platesegmental mandibulectomy

Identifiers

PMID35743379
PMCPMC9224531
OpenAlexW4281638881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.