ArticleJournal of clinical medicine2022
One-Stage Coverage of Leg Region Defects with STSG Combined with VAC Dressing Improves Early Patient Mobilisation and Graft Take: A Comparative Study.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Skin graft bolstered by negative pressure therapy in chronic wounds: A systematic review.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026Pooled it
- Efficacy and safety of combined negative pressure therapy after skin grafting on limbs: A systematic review and meta-analysis.JPRAS open · 2025Review
- A Novel Treatment of Hidradenitis Suppurativa With Radical Unroofing and Deepithelialization.Plastic and reconstructive surgery. Global open · 2025Article
- Application of antibiotic-loaded bone cement in treating lower limb soft tissue infection.Pakistan journal of medical sciences · 2025Article
- Fish Skin Acellular Dermal Matrix Combined With Negative Pressure Wound Therapy for Diabetic Foot Ulcers.Cureus · 2025Article
- Exploring an Innovative Approach: Integrating Negative-Pressure Wound Therapy with Silver Nanoparticle Dressings in Skin Graft Procedures.Journal of personalized medicine · 2024Article
- Revisiting the reconstructive ladder for soft tissue reconstruction in the lower extremity.Annals of translational medicine · 2024Review
- Pressure Ulcers-A Longstanding Problem: A 7-Year Neurorehabilitation Unit Experience of Management, Care, and Clinical Outcomes.Diagnostics (Basel, Switzerland) · 2023Article
- Special Issue "Experimental and Clinical Advances in Skin Grafting".Journal of clinical medicine · 2023Article
- Split thickness skin graft compression: a scoping review.Gland surgery · 2023Article
- Article
- Objective Skin Quality Assessment after Reconstructive Procedures for Facial Skin Defects.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lower limb skin defects are very common and can result from a wide range of aetiologies. Split thickness skin graft (STSG) is a widely used method to address these problems. The role of postoperative dressing is primary as it permits one to apply a uniform pressure over the grafted area and promote adherence. Focusing on lower limb reconstruction, our clinical study compares the application of V.A.C. (Vacuum Assisted Closure) Therapy vs. conventional dressing in the immediate postoperative period following skin grafting. We included in the study all patients who received skin grafts on the leg region between January 2015 and December 2018, despite the aetiology of the defect. Only reconstructions with complete preoperative and postoperative follow-up data were included in the study. Patients were divided into two groups depending on if they received a traditional compressive dressing or a VAC dressing in the immediate postoperative period. We could retain 92 patients, 23 in the No VAC group and 69 in the VAC group. The patients included in the VAC group showed a statistically significant higher rate of graft take together with a lower immobilisation time (p < 0.05). Moreover, a lower rate of postoperative infection was recorded in the VAC group. This study represents the largest in the literature to report in detail surgical outcomes comparing the use of VAC therapy vs. conventional dressing after STSG in the postoperative management of lower limb reconstruction using skin grafts. VAC therapy was used to secure the grafts in the leg region, increasing the early graft take rate while at the same time improving patient mobilisation.
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