Evidence map›Paper›PMID 35743353›Full record

ArticleJournal of clinical medicine2022

Influence of Immunosuppressive Regimen on Diffusivity and Oxygenation of Kidney Transplants-Analysis of Functional MRI Data from the Randomized ZEUS Trial.

Laila-Yasmin Mani, Jasna Cotting, Bruno Vogt, Ute Eisenberger, Peter Vermathen

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00575432 (Evaluation of Kidney Function by Multi-modal Magnetic Resonance Imaging and Spectroscopy in Renal Transplantation and Kidney Disease), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00575432 unknown statusnot on this map

Evaluation of Kidney Function by Multi-modal Magnetic Resonance Imaging and Spectroscopy in Renal Transplantation and Kidney Disease

TypeobservationalSponsorInsel Gruppe AG, University Hospital BernRan2004 to 2024Enrolled200ConditionsKidney Transplantation, Urinary CalculiArmsdiffusion MRI, BOLD MRI, Clinical Outcome
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Magnetic resonance imaging of renal oxygenation.Nature reviews. Nephrology · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laila-Yasmin ManiDepartment of Nephrology and Hypertension, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-4693-7814
Jasna CottingDepartments of Biomedical Research and Radiology, University of Bern, 3010 Bern, Switzerland.
Bruno VogtDepartment of Nephrology and Hypertension, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Ute EisenbergerDepartment of Nephrology, University Hospital Essen, University of Duisburg-Essen, 45127 Essen, Germany.
Peter VermathenDepartments of Biomedical Research and Radiology, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0001-8649-1098

Funding

Swiss National Science Foundation 320000-111959
6 · The paper itself

Abstract

The ZEUS study was a multi-center randomized controlled trial investigating the effect of early conversion from a ciclosporin-based to an everolimus-based regimen on graft function twelve months post-transplantation. In this investigator-initiated sub-study, functional magnetic resonance imaging (fMRI) of kidney grafts was prospectively performed to non-invasively assess differences in graft oxygenation, diffusion and perfusion between groups and time-points using diffusion-weighted imaging (DWI) and blood oxygen level-dependent (BOLD)-MRI. Sixteen patients underwent DWI and BOLD-MRI at months 4.5 and 12 post-transplantation on a 3 Tesla and 1.5 Tesla (

Indexed as

blood oxygen level-dependent (BOLD)calcineurin inhibitorscyclosporindiffusion-weighted imaging (DWI)everolimusfunctional MRIintravoxel incoherent motion imaging (IVIM)kidney transplantationmTOR inhibitorsZEUS study

Identifiers

PMID35743353
PMCPMC9224619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.