Evidence map›Paper›PMID 35743336›Full record

ReviewJournal of clinical medicine2022

Interventional Radiology in the Management of Metastases and Bone Tumors.

Ferruccio Sgalambro, Luigi Zugaro, Federico Bruno, Pierpaolo Palumbo, Nicola Salducca, Carmine Zoccali, Antonio Barile, Carlo Masciocchi, Francesco Arrigoni

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05738941 (Interventional Radiology Strategies in Management of Painful Bony Lesions), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05738941 unknown statusnot on this mapstarted 2025, after this paper: background citation

Interventional Radiology Strategies in Management of Painful Bony Lesions

TypeobservationalSponsorAssiut UniversityRan2025 to 2025Enrolled50ConditionsBone LesionArmsradiofrequency ablation, angioembolization
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Thyroid-Targeted Nano-Bombs Empower HIFU for Graves' Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  11. Review
  12. Review
  13. Effectiveness of RF ablation and cementoplasty in enhancing functional capacity in pelvic malignant bone metastases.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Article
  14. Tissue Ablation: Applications and Perspectives.Advanced materials (Deerfield Beach, Fla.) · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Thermal necrosis in orthopedic bone tumors: experimental research.Annals of medicine and surgery (2012) · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ferruccio SgalambroDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Luigi ZugaroSan Salvatore Hospital, 67100 L'Aquila, Italy.
Federico BrunoSan Salvatore Hospital, 67100 L'Aquila, Italy.ORCID 0000-0002-1444-2585
Pierpaolo PalumboSan Salvatore Hospital, 67100 L'Aquila, Italy.ORCID 0000-0003-1514-0092
Nicola SalduccaOncological Orthopaedics Unit, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Carmine ZoccaliOncological Orthopaedics Unit, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.ORCID 0000-0001-8847-6772
Antonio BarileDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Carlo MasciocchiDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Francesco ArrigoniSan Salvatore Hospital, 67100 L'Aquila, Italy.ORCID 0000-0001-7793-1872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interventional Radiology (IR) has experienced an exponential growth in recent years. Technological advances of the last decades have made it possible to use new treatments on a larger scale, with good results in terms of safety and effectiveness. In musculoskeletal field, painful bone metastases are the most common target of IR palliative treatments; however, in selected cases of bone metastases, IR may play a curative role, also in combination with other techniques (surgery, radiation and oncology therapies, etc.). Primary malignant bone tumors are extremely rare compared with secondary bone lesions: osteosarcoma, Ewing sarcoma, and chondrosarcoma are the most common; however, the role of interventional radiology in this fiels is marginal. In this review, the main techniques used in interventional radiology were examined, and advantages and limitations illustrated. Techniques of ablation (Radiofrequency, Microwaves, Cryoablation as also magnetic resonance imaging-guided high-intensity focused ultrasound), embolization, and Cementoplasty will be described. The techniques of ablation work by destruction of pathological tissue by thermal energy (by an increase of temperature up to 90 °C with the exception of the Cryoablation that works by freezing the tissue up to -40 °C). Embolization creates an ischemic necrosis by the occlusion of the arterial vessels that feed the tumor. Finally, cementoplasty has the aim of strengthening bone segment weakened by the growth of pathological tissue through the injection of cement. The results of the treatments performed so far were also assessed and presented focused the attention on the management of bone metastasis.

Indexed as

bone metastaseselectrochemotherapyinterventional radiologymagnetic resonance imaging-guided high-intensity focused ultrasoundthermal ablationtumour embolization

Identifiers

PMID35743336
PMCPMC9225477

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.