Evidence map›Paper›PMID 35743309›Full record

ArticleInternational journal of molecular sciences2022

Diterpenoid Caesalmin C Delays Aβ-Induced Paralysis Symptoms via the DAF-16 Pathway in

Zong-Ping Zhang, Xue Bai, Wen-Bo Cui, Xiao-Han Chen, Xu Liu, De-Juan Zhi, Zhan-Xin Zhang, Dong-Qing Fei, Dong-Sheng Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. International journal of molecular sciences · 2025
    Article
  3. Synergetic effect of β-asarone and cannabidiol against Aβ aggregationComputational and structural biotechnology journal · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zong-Ping ZhangSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Xue BaiSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Wen-Bo CuiSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Xiao-Han ChenSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Xu LiuSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
De-Juan ZhiSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Zhan-Xin ZhangSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Dong-Qing FeiSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0002-5332-8347
Dong-Sheng WangSchool of Pharmacy, Lanzhou University, Lanzhou 730000, China.

Funding

National Natural Science Foundation of China 31670350National Natural Science Foundation of China 31870324Natural Science Foundation of Gansu Province 21JR7RA444Natural Science Foundation of Gansu Province 21JR7RA477
6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the world. However, there is no effective drug to cure it. Caesalmin C is a cassane-type diterpenoid abundant in

Indexed as

Alzheimer DiseaseCaenorhabditis elegans ProteinsDiterpenesNeurodegenerative DiseasesAcetylcholinesteraseAmyloid beta-PeptidesAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansDisease Models, AnimalForkhead Transcription FactorsParalysisRNA, MessengerAcetylcholinesteraseAmyloid beta-PeptidesCaenorhabditis elegans Proteinsdaf-16 protein, C elegansDiterpenesForkhead Transcription FactorsRNA, MessengerAlzheimer’s diseaseamyloid β-proteinCaenorhabditis eleganscaesalmin CDAF-16

Identifiers

PMID35743309
PMCPMC9225120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.