Evidence map›Paper›PMID 35743281›Full record

ArticleInternational journal of molecular sciences2022

Effects of Ultrafine Single-Nanometer Oxygen Bubbles on Radiation Sensitivity in a Tumor-Bearing Mouse Model.

Navchaa Gombodorj, Takehiko Yokobori, Nobutoshi Mutsuki, Bilguun Erkhem-Ochir, Haruka Okami, Takayuki Asao, Hiroshi Saeki, Ken Shirabe, Dai Yamanouchi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Navchaa GombodorjDivision of Integrated Oncology Research, Gunma University Initiative for Advanced Research (GIAR), 3-39-22 Showamachi, Maebashi 371-8511, Japan.ORCID 0000-0001-9290-3706
Takehiko YokoboriDivision of Integrated Oncology Research, Gunma University Initiative for Advanced Research (GIAR), 3-39-22 Showamachi, Maebashi 371-8511, Japan.ORCID 0000-0003-3284-4796
Nobutoshi MutsukiSigma Technology Inc., 1-11-29 Sotono, Hitachinaka 312-0053, Japan.
Bilguun Erkhem-OchirDivision of Integrated Oncology Research, Gunma University Initiative for Advanced Research (GIAR), 3-39-22 Showamachi, Maebashi 371-8511, Japan.
Haruka OkamiDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi 371-8510, Japan.
Takayuki AsaoGunma University Center for Mathematics and Data Science, 4-2 Aramaki, Maebashi 371-8510, Japan.
Hiroshi SaekiDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi 371-8510, Japan.
Ken ShirabeDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, Maebashi 371-8510, Japan.
Dai YamanouchiDivision of Vascular Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53726, USA.
Gunma University · JPHitachi (Japan) · JPUniversity of Wisconsin–Madison · US

Funding

Japan Society for the Promotion of Science 18K07665
6 · The paper itself

Abstract

Radiation therapy against cancer cells often causes radiation resistance via accumulation of hypoxia-inducible factor 1 subunit alpha (HIF-1α) under hypoxic conditions and severe side effects. Radiation sensitizers without side effects are required to overcome hypoxia-induced radiation resistance and decrease radiation-related side effects in patients with refractory cancer. We previously developed oxygen nanobubble water (NBO

Indexed as

OxygenRadiation-Sensitizing AgentsAnimalsCell HypoxiaCell Line, TumorDisease Models, AnimalFemaleHumansHypoxiaHypoxia-Inducible Factor 1, alpha SubunitMiceMice, Inbred BALB CRadiation ToleranceWaterHypoxia-Inducible Factor 1, alpha SubunitOxygenRadiation-Sensitizing AgentsWaterHIFshypoxiaradiation sensitizertumor-bearing mouse modelultrafine nanobubble oxygen

Identifiers

PMID35743281
PMCPMC9224848
OpenAlexW4283206511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.