Evidence map›Paper›PMID 35743253›Full record

ArticleInternational journal of molecular sciences2022

Silencing the

Li-Bin Wang, Li-Jian Chen, Qi Wang, Xiao-Li Xie

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. A Mechanistic Review on Toxicity Effects of Methamphetamine.International journal of medical sciences · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Molecular Mechanisms of Hepatotoxicity.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Li-Bin WangDepartment of Toxicology, School of Public Health (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, No. 1838 North Guangzhou Road, Guangzhou 510515, China.
Li-Jian ChenDepartment of Forensic Pathology, School of Forensic Medicine, Southern Medical University, No. 1838 North Guangzhou Road, Guangzhou 510515, China.
Qi WangDepartment of Forensic Pathology, School of Forensic Medicine, Southern Medical University, No. 1838 North Guangzhou Road, Guangzhou 510515, China.ORCID 0000-0002-1556-2167
Xiao-Li XieDepartment of Toxicology, School of Public Health (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, No. 1838 North Guangzhou Road, Guangzhou 510515, China.
Southern Medical University · CN

Funding

Department of Science and Technology of Guangzhou city 202002030043Guangdong Basic and Applied Basic Research Foundation 2020A1515010370Guangdong Basic and Applied Basic Research Foundation 2021A1515012456National Natural Science Foundation of China 82171877
6 · The paper itself

Abstract

Methamphetamine (METH) is a stimulant drug. METH abuse induces hepatotoxicity, although the mechanisms are not well understood. METH-induced hepatotoxicity was regulated by TLR4-mediated inflammation in BALB/c mice in our previous study. To further investigate the underlying mechanisms, the wild-type (C57BL/6) and

Indexed as

Chemical and Drug Induced Liver InjuryMethamphetamineAnimalsAnti-Bacterial AgentsInflammationLipopolysaccharidesMiceMice, Inbred C57BLNF-kappa BRNAToll-Like Receptor 4Anti-Bacterial AgentsLipopolysaccharidesMethamphetamineNF-kappa BRNATlr4 protein, mouseToll-Like Receptor 4hepatotoxicityinflammationmethamphetamineTLR4 pathway

Identifiers

PMID35743253
PMCPMC9224410
OpenAlexW4283120859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.