Evidence map›Paper›PMID 35743168›Full record

ArticleInternational journal of molecular sciences2022

Hypercholesterolemia Negatively Regulates P2X7-Induced Cellular Function in CD4

Tom Hutteau-Hamel, Amine Mellouk, Nicolas Trainel, Anne-Marie Cassard, Pierre Bobé

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Purinergic Signalling in Physiology and Pathophysiology.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tom Hutteau-HamelInstitut National de la Santé et de la Recherche Médicale-INSERM, Université Paris-Saclay, UMR 996, 92140 Clamart, France.
Amine MelloukInstitut National de la Santé et de la Recherche Médicale-INSERM, Université Paris-Saclay, UMR 996, 92140 Clamart, France.
Nicolas TrainelInstitut National de la Santé et de la Recherche Médicale-INSERM, Université Paris-Saclay, UMR 996, 92140 Clamart, France.
Anne-Marie CassardInstitut National de la Santé et de la Recherche Médicale-INSERM, Université Paris-Saclay, UMR 996, 92140 Clamart, France.ORCID 0000-0002-1813-5128
Pierre BobéInstitut National de la Santé et de la Recherche Médicale-INSERM, Université Paris-Saclay, UMR 996, 92140 Clamart, France.
Inserm · FR

Funding

Agence Nationale de la Recherche ANR-13-ISV6-0003
6 · The paper itself

Abstract

We have previously showed that plasma membrane cholesterol and GM1 ganglioside content are responsible for the opposite sensitivity of mouse leukemic T cells to ATP. We also reported that the sensitivity of CD4

Indexed as

CD8-Positive T-LymphocytesHypercholesterolemiaAdenosine TriphosphateAnimalsCD4-Positive T-LymphocytesCholesterolDiet, High-FatG(M1) GangliosideMiceReceptors, Purinergic P2X7T-Lymphocyte SubsetsAdenosine TriphosphateCholesterolG(M1) GangliosideReceptors, Purinergic P2X7cholesterolhigh fat dietP2X7 receptorT-cell subsets

Identifiers

PMID35743168
PMCPMC9223416
OpenAlexW4283030929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.