Evidence map›Paper›PMID 35743144›Full record

ArticleInternational journal of molecular sciences2022

Cichoric Acid May Play a Role in Protecting Hair Cells from Ototoxic Drugs.

Ting-Wei Lai, Hsin-Lin Cheng, Tzu-Rong Su, Jiann-Jou Yang, Ching-Chyuan Su

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Antioxidants (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ting-Wei LaiDepartment of BioMedical Sciences, Chung Shan Medical University, Taichung 402, Taiwan.
Hsin-Lin ChengDepartment of BioMedical Sciences, Chung Shan Medical University, Taichung 402, Taiwan.
Tzu-Rong SuAntai Medical Care Corporation Antai Tian-Sheng Memorial Hospital, Pingtung 928, Taiwan.
Jiann-Jou YangDepartment of BioMedical Sciences, Chung Shan Medical University, Taichung 402, Taiwan.ORCID 0000-0002-9019-2178
Ching-Chyuan SuAntai Medical Care Corporation Antai Tian-Sheng Memorial Hospital, Pingtung 928, Taiwan.
Chung Shan Medical University · TWMeiho University · TWChung Shan Medical University Hospital · TW

Funding

Chung Shan Medical University, Tian-Sheng Memorial Hospital CSMU-TSMH-106-01Ministry of Science and Technology MOST 107-2320-B-040-027-MY3 and 110-2320-B-040 -011 -MY3
6 · The paper itself

Abstract

Ototoxic hearing loss due to antibiotic medication including aminoglycosides and excess free radical production causes irreversible hair cell injury. Cichoric acid, a naturally occurring phenolic acid, has recently been found to exert anti-oxidative and anti-inflammatory properties through its free radical scavenging capacity. The present study aimed to investigate the protective effects of cichoric acid against neomycin-induced ototoxicity using transgenic zebrafish (

Indexed as

OtotoxicityZebrafishAnimalsAnimals, Genetically ModifiedAnti-Bacterial AgentsCaffeic AcidsHairMechanotransduction, CellularNeomycinSuccinatesAnti-Bacterial AgentsCaffeic Acidschicoric acidNeomycinSuccinatesanti-oxidantcichoric acid (CA)hair cellzebrafish

Identifiers

PMID35743144
PMCPMC9224198
OpenAlexW4283017378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.