Evidence map›Paper›PMID 35743116›Full record

ArticleInternational journal of molecular sciences2022

Preparation of Calcium Phosphate Compounds on Zirconia Surfaces for Dental Implant Applications.

Mei-Shuan Cheng, Eisner Salamanca, Jerry Chin-Yi Lin, Yu-Hwa Pan, Yi-Fan Wu, Nai-Chia Teng, Ikki Watanabe, Ying-Sui Sun, Wei-Jen Chang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Bone Regeneration: Mini-Review and Appealing Perspectives.Bioengineering (Basel, Switzerland) · 2025
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Mei-Shuan ChengSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Eisner SalamancaSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Jerry Chin-Yi LinSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Yu-Hwa PanSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Yi-Fan WuSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-8872-6014
Nai-Chia TengSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Ikki WatanabeDepartment of Gerodontology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Ying-Sui SunSchool of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-6128-9886
Wei-Jen ChangSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Taipei Medical University · TWChang Gung University · TWHarvard University · USTaipei Medical University Hospital · TWTaipei Medical University-Shuang Ho Hospital · TWTokyo Medical and Dental University · JP

Funding

Ministry of Science and Technology of the People's Republic of China (MOST 107-2321-B-038-007-MY3Ministry of Science and Technology of the People's Republic of China MOST 110-2314-B-038-029-Ministry of Science and Technology of the People's Republic of China MOST 110-2314-B-038-065-MY3
6 · The paper itself

Abstract

Titanium is widely used in medical implants despite the release of heavy metal ions over long-term use. Zirconia is very close to the color of teeth; however, its biological inertness hinders bonding with bone tissue. Alkaline treatment and coatings of calcium phosphate can be used to enhance bone regeneration adjacent to dental implants. This study examined the effects of alkaline treatment, calcium phosphate coatings, and sintering, on the physical properties of implant material. Our analysis confirmed that the calcium phosphate species were octacalcium phosphate (OCP). The sintering of calcium phosphate was shown to create B-type HAP, which is highly conducive toward the differentiation of mesenchymal stem cells (MSCs) into osteoblasts for the facilitation of bone integration. Conclusions: This study demonstrated the room-temperature fabrication of dental implants with superhydrophilic surfaces to enhance biocompatibility.

Indexed as

Coated Materials, BiocompatibleDental ImplantsCalcium PhosphatesOsseointegrationPhosphatesSurface PropertiesTitaniumZirconiumCalcium PhosphatesCoated Materials, BiocompatibleDental ImplantsPhosphatesTitaniumZirconiumzirconium oxidealkali treatmentcalcium phosphate coatingsinteringsurface modificationzirconia

Identifiers

PMID35743116
PMCPMC9223636
OpenAlexW4282968427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.