Evidence map›Paper›PMID 35743110›Full record

ArticleInternational journal of molecular sciences2022

Dispirooxindole-β-Lactams: Synthesis via Staudinger Ketene-Imine Cycloaddition and Biological Evaluation.

Vadim E Filatov, Dmitrii A Iuzabchuk, Viktor A Tafeenko, Yuri K Grishin, Vitaly A Roznyatovsky, Dmitrii A Lukianov, Yulia A Fedotova, Maxim A Sukonnikov, Dmitry A Skvortsov, Nikolai V Zyk and 1 more

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vadim E FilatovDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.
Dmitrii A IuzabchukDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.ORCID 0000-0001-9939-7762
Viktor A TafeenkoDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.
Yuri K GrishinDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.
Vitaly A RoznyatovskyDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.ORCID 0000-0002-5673-8931
Dmitrii A LukianovDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.
Yulia A FedotovaDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.
Maxim A SukonnikovDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.
Dmitry A SkvortsovDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.
Nikolai V ZykDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.
Elena K BeloglazkinaDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, 119234 Moscow, Russia.ORCID 0000-0001-6796-8241

Funding

Russian Foundation for Basic Research 19-33-90282Russian Science Foundation 21-13-00023Russian Science Foundation 22-14-00099
6 · The paper itself

Abstract

In this work, we present the first synthesis of dispirooxindole-β-lactams employing optimized methodology of

Indexed as

beta-LactamsIminesCycloaddition ReactionEscherichia coliEthylenesHEK293 CellsHumansKetonesbeta-LactamsEthylenesIminesketeneKetonesketene-imine cycloadditionoxo-pyrrolidine-3-carboxylic acidsspirooxindolesStaudinger reactionβ-lactams

Identifiers

PMID35743110
PMCPMC9223813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.