ReviewInternational journal of molecular sciences2022
Metabolic Characteristics of Hashimoto's Thyroiditis Patients and the Role of Microelements and Diet in the Disease Management-An Overview.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
72 citing papers in PubMed, 6 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Pooled it
- Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Exploring the role of gut microbiota in autoimmune thyroid disorders: a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Vitamin D-Related Genes and Thyroid Cancer-A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Microbiota Alterations in Patients with Autoimmune Thyroid Diseases: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Global prevalence and epidemiological trends of Hashimoto's thyroiditis in adults: A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- The Combined Effects of an Anti-Inflammatory Diet and Curcumin Supplementation on Thyroid Function and Lipid Profile in Patients With Hashimoto's Thyroiditis: A Double Blind Randomised Clinical Trial.Endocrinology, diabetes & metabolism · 2026Trial
- The causal relationship between diabetes mellitus and hashimoto thyroiditis: A two-sample mendelian randomization analysis.Medicine · 2026Article
- Effects of plant flavonoids and selenium on pancreatic hormones and glucose homeostasis in autoimmune thyroiditis.Experimental animals · 2026Article
- Review
- Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto's thyroiditis.Gland surgery · 2026Review
- Risk of Functional Disorders and/or Thyroid Autoimmunity and Its Association with 25OH Vitamin D and Magnesium Levels: A Population-Based Case-Control Study.Medical sciences (Basel, Switzerland) · 2026Article
- Different fatty acid patterns in serum in patients with various thyroid diseases.Scientific reports · 2026Article
- Vitamin A and E status across the spectrum of Hashimoto's thyroiditis in women: associations with autoimmunity and thyroid function.Frontiers in nutrition · 2026Article
- The role of gut microbiota in autoimmune thyroid diseases: nutritional determinants and diet-based modulation.Frontiers in endocrinology · 2026Review
- The Impact of Selenium Deficiency and Supplementation on Hashimoto's Thyroiditis: A Clinical Evaluation.Endocrine, metabolic & immune disorders drug targets · 2026Article
- Coexistent Hashimoto's thyroiditis modulates lymph node metastasis burden in papillary thyroid carcinoma: a single-center study in South China.Frontiers in endocrinology · 2026Article
- Association between anti-nuclear antibody (ANA) positivity and autoimmune thyroid disease markers in a general examination population.Biochemistry and biophysics reports · 2025Article
- Vitamin D Receptor Polymorphisms and Immunological Effects of Vitamin D in Hashimoto's Thyroiditis.International journal of molecular sciences · 2025Review
- Unveiling the Connection Between Micronutrients and Autoimmune Thyroiditis: Are They True Friends?Biological trace element research · 2025Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Hashimoto's thyroiditis (HT) is the most common autoimmune disease and the leading cause of hypothyroidism, in which damage to the thyroid gland occurs due to the infiltration of lymphocytes. It is characterized by increased levels of antibodies against thyroid peroxidase and thyroglobulin. In this review, we present the metabolic profile, the effectiveness of micronutrient supplementation and the impact of dietary management in patients with HT. For this current literature review, the databases PubMed, Cochrane, Medline and Embase were reviewed from the last ten years until March 2022. This article provides a comprehensive overview of recent randomized controlled trials, meta-analyses, and clinical trials. Many patients with HT, even in the euthyroid state, have excess body weight, metabolic disorders, and reduced quality of life. Due to frequent concomitant nutritional deficiencies, the role of vitamin D, iodine, selenium, magnesium, iron and vitamin B12 is currently debated. Several studies have underlined the benefits of vitamin D and selenium supplementation. There is still no specific diet recommended for patients with HT, but a protective effect of an anti-inflammatory diet rich in vitamins and minerals and low in animal foods has been suggested. There is insufficient evidence to support a gluten-free diet for all HT patients. Pharmacotherapy, along with appropriate nutrition and supplementation, are important elements of medical care for patients with HT. The abovementioned factors may decrease autoantibody levels, improve thyroid function, slow down the inflammatory process, maintain proper body weight, relieve symptoms, and prevent nutritional deficiencies and the development of metabolic disorders in patients with HT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.