Evidence map›Paper›PMID 35743006›Full record

ReviewInternational journal of molecular sciences2022

A Guide to Polysaccharide-Based Hydrogel Bioinks for 3D Bioprinting Applications.

Maria C Teixeira, Nicole S Lameirinhas, João P F Carvalho, Armando J D Silvestre, Carla Vilela, Carmen S R Freire

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Diversification of biofilm architecture among freshwaterApplied and environmental microbiology · 2026
    Article
  2. Aerosol Jet Printing in Biotechnologies.Bioengineering (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Double-Network Polysaccharide-Collagen Hybrid Bioink.ACS applied materials & interfaces · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Natural Regenerative Hydrogels for Wound Healing.Gels (Basel, Switzerland) · 2024
    Review
  15. Article
  16. Review
  17. Review
  18. Unlocking the Potential of Stem Cell Microenvironments In Vitro.Bioengineering (Basel, Switzerland) · 2024
    Review
  19. Review
  20. Reasoning on Pore Terminology in 3D Bioprinting.Gels (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria C TeixeiraCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-5306-1996
Nicole S LameirinhasCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
João P F CarvalhoCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-3166-450X
Armando J D SilvestreCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-5403-8416
Carla VilelaCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-9212-2704
Carmen S R FreireCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-6320-4663

Funding

Fundação para a Ciência e Tecnologia 2020.09018.BDFundação para a Ciência e Tecnologia CEECIND/00263/2018 and 2021.01571.CEECINDFundação para a Ciência e Tecnologia CEECIND/00464/2017Fundação para a Ciência e Tecnologia project NANOBIOINKS (CENTRO-01-0145-FEDER-031289)Fundação para a Ciência e Tecnologia SFRH/BD/140229/2018Fundação para a Ciência e Tecnologia UIDB/50011/2020, UIDP/50011/2020 & LA/P/0006/2020
6 · The paper itself

Abstract

Three-dimensional (3D) bioprinting is an innovative technology in the biomedical field, allowing the fabrication of living constructs through an approach of layer-by-layer deposition of cell-laden inks, the so-called bioinks. An ideal bioink should possess proper mechanical, rheological, chemical, and biological characteristics to ensure high cell viability and the production of tissue constructs with dimensional stability and shape fidelity. Among the several types of bioinks, hydrogels are extremely appealing as they have many similarities with the extracellular matrix, providing a highly hydrated environment for cell proliferation and tunability in terms of mechanical and rheological properties. Hydrogels derived from natural polymers, and polysaccharides, in particular, are an excellent platform to mimic the extracellular matrix, given their low cytotoxicity, high hydrophilicity, and diversity of structures. In fact, polysaccharide-based hydrogels are trendy materials for 3D bioprinting since they are abundant and combine adequate physicochemical and biomimetic features for the development of novel bioinks. Thus, this review portrays the most relevant advances in polysaccharide-based hydrogel bioinks for 3D bioprinting, focusing on the last five years, with emphasis on their properties, advantages, and limitations, considering polysaccharide families classified according to their source, namely from seaweed, higher plants, microbial, and animal (particularly crustaceans) origin.

Indexed as

BioprintingAnimalsHydrogelsInkPolysaccharidesPrinting, Three-DimensionalTissue EngineeringTissue ScaffoldsHydrogelsPolysaccharides3D bioprintingbioinkscell-laden constructshydrogelspolysaccharides

Identifiers

PMID35743006
PMCPMC9223682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.