Evidence map›Paper›PMID 35742841›Full record

ArticleInternational journal of molecular sciences2022

Transcriptome and Proteome Analyses Reveal Stage-Specific DNA Damage Response in Embryos of Sturgeon (

Ievgeniia Gazo, Ravindra Naraine, Ievgen Lebeda, Aleš Tomčala, Mariola Dietrich, Roman Franěk, Martin Pšenička, Radek Šindelka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. DNA repair genes play a variety of roles in the development of fish embryos.Frontiers in cell and developmental biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ievgeniia GazoSouth Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in České Budějovice, Zátiší 728/II, 389 25 Vodňany, Czech Republic.ORCID 0000-0003-3098-1666
Ravindra NaraineLaboratory of Gene Expression, Institute of Biotechnology-Biocev, Academy of Science of Czech Republic, 252 50 Vestec, Czech Republic.
Ievgen LebedaSouth Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in České Budějovice, Zátiší 728/II, 389 25 Vodňany, Czech Republic.ORCID 0000-0002-5423-8562
Aleš TomčalaInstitute of Aquaculture and Protection of Waters, Faculty of Fisheries and Protection of Waters, University of South Bohemia in České Budějovice, Husova tř. 458/102, 370 05 České Budějovice, Czech Republic.
Mariola DietrichDepartment of Gametes and Embryo Biology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, 10-748 Olsztyn, Poland.ORCID 0000-0002-2525-0941
Roman FraněkSouth Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in České Budějovice, Zátiší 728/II, 389 25 Vodňany, Czech Republic.ORCID 0000-0002-3464-1872
Martin PšeničkaSouth Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in České Budějovice, Zátiší 728/II, 389 25 Vodňany, Czech Republic.
Radek ŠindelkaLaboratory of Gene Expression, Institute of Biotechnology-Biocev, Academy of Science of Czech Republic, 252 50 Vestec, Czech Republic.
University of South Bohemia in České Budějovice · CZCzech Academy of Sciences, Institute of Biotechnology · CZInLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences · PL

Funding

Czech Science Foundation GAČR 19-11140YCzech Science Foundation GAČR 19-11313SMinistry of Education, Youth and Sports of the Czech Republic "CENAKAVA Center Development" (CZ.1.05/2.1.00/19.0380)Ministry of Education, Youth and Sports of the Czech Republic "CENAKVA" (LM2018099)Ministry of Education, Youth and Sports of the Czech Republic CZ.02.1.01/0.0/0.0/16_025/0007370RVO 86652036
6 · The paper itself

Abstract

DNA damage during early life stages may have a negative effect on embryo development, inducing mortality and malformations that have long-lasting effects during adult life. Therefore, in the current study, we analyzed the effect of DNA damage induced by genotoxicants (camptothecin (CPT) and olaparib) at different stages of embryo development. The survival, DNA fragmentation, transcriptome, and proteome of the endangered sturgeon

Indexed as

ProteomeTranscriptomeAnimalsDNA DamageFishesMaleProteomicsSemenProteomeDNA damage responseembryofishomicssturgeon

Identifiers

PMID35742841
PMCPMC9223696
OpenAlexW4281669076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.