Evidence map›Paper›PMID 35742831›Full record

ArticleInternational journal of molecular sciences2022

CRISPR/Cas9-Directed Gene Trap Constitutes a Selection System for Corrected

Elena Vuelta, José L Ordoñez, David J Sanz, Sandra Ballesteros, Jesús M Hernández-Rivas, Lucía Méndez-Sánchez, Manuel Sánchez-Martín, Ignacio García-Tuñón

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Targeted disruption of theActa biochimica et biophysica Sinica · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Advances in Molecular Research of Oncogenes.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Elena VueltaDepartamento de Medicina, Universidad de Salamanca, 37007 Salamanca, Spain.
José L OrdoñezInstituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.
David J SanzUnidad de Diagnóstico Molecular y Celular del Cáncer, Instituto Biología Molecular y Celular del Cáncer (USAL/CSIC), 37007 Salamanca, Spain.
Sandra BallesterosDepartamento de Medicina, Universidad de Salamanca, 37007 Salamanca, Spain.
Jesús M Hernández-RivasDepartamento de Medicina, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-9661-9371
Lucía Méndez-SánchezServicio de Transgénesis, NUCLEUS, Universidad de Salamanca, 37007 Salamanca, Spain.
Manuel Sánchez-MartínDepartamento de Medicina, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-8370-1336
Ignacio García-TuñónDepartamento de Medicina, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0003-4758-2151
Universidad de Salamanca · ESCentro de Investigación del Cáncer · ES

Funding

Bomberos Ayudan Fundation Jabones Solidarios para DanielFundación Mutua Madrileña AP176752021Instituto de Salud Carlos III PI17/01895Instituto de Salud Carlos III PI18/01500Instituto de Salud Carlos III PI21/00983Instituto de Salud Carlos III PI22/00694Junta de Castilla y León SA118P20University of Salamanca Fundación Samuel Solórzano FS/29-2020University of Salamanca Predoctoral Grant of Elena Vuelta
6 · The paper itself

Abstract

Chronic myeloid leukaemia (CML) is a haematological neoplasm driven by the

Indexed as

Fusion Proteins, bcr-ablLeukemia, Myelogenous, Chronic, BCR-ABL PositiveApoptosisCell ProliferationChronic DiseaseCRISPR-Cas SystemsHumansFusion Proteins, bcr-ablBCR/ABLchronic myeloid leukaemiaCRISPRCRISPR-Trapgene therapy

Identifiers

PMID35742831
PMCPMC9224210
OpenAlexW4281666352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.