Evidence map›Paper›PMID 35742213›Full record

ArticleInternational journal of environmental research and public health2022

The Impact of World Trade Center Related Medical Conditions on the Severity of COVID-19 Disease and Its Long-Term Sequelae.

Elizabeth Lhuillier, Yuan Yang, Olga Morozova, Sean A P Clouston, Xiaohua Yang, Monika A Waszczuk, Melissa A Carr, Benjamin J Luft

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Association of COVID-19 Severity with Comorbidities: Results from the World Trade Center Health Registry.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Elizabeth LhuillierDepartment of Medicine, Renaissance School of Medicine, Stony Brook University (SUNY), Stony Brook, NY 11794, USA.
Yuan YangProgram in Public Health, Stony Brook University (SUNY), Stony Brook, NY 11794, USA.
Olga MorozovaProgram in Public Health, Stony Brook University (SUNY), Stony Brook, NY 11794, USA.ORCID 0000-0001-7606-8413
Sean A P CloustonProgram in Public Health, Stony Brook University (SUNY), Stony Brook, NY 11794, USA.ORCID 0000-0002-6124-0329
Xiaohua YangDepartment of Medicine, Renaissance School of Medicine, Stony Brook University (SUNY), Stony Brook, NY 11794, USA.ORCID 0000-0002-1508-7220
Monika A WaszczukDepartment of Psychology, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.
Melissa A CarrWorld Trade Center Health and Wellness Program, Stony Brook University (SUNY), Stony Brook, NY 11794, USA.ORCID 0000-0002-0870-6628
Benjamin J LuftDepartment of Medicine, Renaissance School of Medicine, Stony Brook University (SUNY), Stony Brook, NY 11794, USA.
Stony Brook School · USStony Brook University · USRosalind Franklin University of Medicine and Science · US

Funding

A lifecourse approach to PTSD and cognitive aging: A cohort of 9/11 respondersR01AG049953 · NIA · STATE UNIVERSITY NEW YORK STONY BROOK · PI CLOUSTON, SEAN · 2015 to 2024
$11.0M
Severity and long-term health effects of COVID-19 among World Trade Center respondersU01OH012275 · OH · STATE UNIVERSITY NEW YORK STONY BROOK · PI LUFT, BENJAMIN J · 2021 to 2025
$2.9M
NIA NIH HHS R01 AG049953NIOSH CDC HHS U01 OH012275NIOSH CDC HHS U01-OH012275
6 · The paper itself

Abstract

The individuals who served our country in the aftermath of the attacks on the World Trade Center (WTC) following the attacks of 11 September 2001 have, since then, been diagnosed with a number of conditions as a result of their exposures. In the present study, we sought to determine whether these conditions were risk factors for increased COVID-19 disease severity within a cohort of N = 1280 WTC responders with complete information on health outcomes prior to and following COVID-19 infection. We collected data on responders diagnosed with COVID-19, or had evidence of receiving positive SARS-CoV-2 polymerase chain reaction or antigen testing, or were asymptomatic but had IgG positive antibody testing. The presence of post-acute COVID-19 sequelae was measured using self-reported symptom severity scales. Analyses revealed that COVID-19 severity was associated with age, Black race, obstructive airway disease (OAD), as well as with worse self-reported depressive symptoms. Similarly, post-acute COVID-19 sequelae was associated with initial analysis for COVID-19 severity, upper respiratory disease (URD), gastroesophageal reflux disease (GERD), OAD, heart disease, and higher depressive symptoms. We conclude that increased COVID-19 illness severity and the presence of post-acute COVID-19 sequelae may be more common in WTC responders with chronic diseases than in those responders without chronic disease processes resulting from exposures at the WTC disaster.

Indexed as

COVID-19DisastersLung Diseases, ObstructiveSeptember 11 Terrorist AttacksCohort StudiesDisease ProgressionHumansSARS-CoV-29/11 disastercomorbiditiesCOVID-19post-acute COVID-19 syndromeSARS-CoV-2severity

Identifiers

PMID35742213
PMCPMC9222715
OpenAlexW4281767188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.