Evidence map›Paper›PMID 35742183›Full record

ArticleHealthcare (Basel, Switzerland)2022

Acute Supplementation with Cannabidiol Does Not Attenuate Inflammation or Improve Measures of Performance following Strenuous Exercise.

Brett W Crossland, B Rhett Rigby, Anthony A Duplanty, George A King, Shanil Juma, Nicholas A Levine, Cayla E Clark, Kyndall P Ramirez, Nicole L Varone

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  5. Review
  6. Article
  7. Review
  8. Article
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  10. Article
  11. Edible marijuana and cycle ergometer exercise.Frontiers in physiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Brett W CrosslandExercise Physiology Laboratory, School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA.
B Rhett RigbyExercise Physiology Laboratory, School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA.
Anthony A DuplantyExercise Physiology Laboratory, School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA.ORCID 0000-0002-3506-048X
George A KingExercise Physiology Laboratory, School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA.
Shanil JumaExercise Physiology Laboratory, School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA.
Nicholas A LevineExercise Physiology Laboratory, School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA.
Cayla E ClarkExercise Physiology Laboratory, School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA.ORCID 0000-0002-5252-8814
Kyndall P RamirezExercise Physiology Laboratory, School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA.
Nicole L VaroneExercise Physiology Laboratory, School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX 76204, USA.
Texas Woman's University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Supplementation with cannabidiol (CBD) may expedite recovery when consumed after exercise. The purpose of this study was to determine if supplementation with CBD reduces inflammation and enhances performance following strenuous eccentric exercise in collegiate athletes. Twenty-four well-trained females (age = 21.2 ± 1.8 years, height = 166.4 ± 8 cm, weight = 64.9 ± 9.1 kg) completed 100 repetitions of unilateral eccentric leg extension to induce muscle damage. In this crossover design, participants were randomized to receive 5 mg/kg of CBD in pill form or a placebo 2 h prior to, immediately following, and 10 h following muscle damage. Blood was collected, and performance and fatigue were measured prior to, and 4 h, 24 h, and 48 h following the muscle damage. Approximately 28 days separated treatment administration to control for the menstrual cycle. No significant differences were observed between the treatments for inflammation, muscle damage, or subjective fatigue. Peak torque at 60°/s (

Indexed as

anti-inflammatoryathletescytokineseccentric exercisefatiguehempmuscle damage

Identifiers

PMID35742183
PMCPMC9222918
OpenAlexW4283031725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.