Evidence map›Paper›PMID 35742003›Full record

ArticleFoods (Basel, Switzerland)2022

Bioactive Compounds and Antioxidant Activity of Red and White Wines Produced from Autochthonous Croatian Varieties: Effect of Moderate Consumption on Human Health.

Sanja Radeka, Sara Rossi, Ena Bestulić, Irena Budić-Leto, Karin Kovačević Ganić, Ivana Horvat, Igor Lukić, Fumica Orbanić, Teodora Zaninović Jurjević, Štefica Dvornik

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Effect of Wine Yeast (Foods (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sanja RadekaInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, Croatia.ORCID 0000-0002-3869-1412
Sara RossiInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, Croatia.ORCID 0000-0003-2691-0662
Ena BestulićInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, Croatia.ORCID 0000-0001-9203-3958
Irena Budić-LetoInstitute for Adriatic Crops and Karst Reclamation, Put Duilova 11, 21000 Split, Croatia.
Karin Kovačević GanićFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia.
Ivana HorvatInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, Croatia.ORCID 0000-0002-1067-9358
Igor LukićInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, Croatia.ORCID 0000-0002-6611-4313
Fumica OrbanićInstitute of Agriculture and Tourism, Karla Huguesa 8, 52440 Poreč, Croatia.ORCID 0000-0002-5343-4617
Teodora Zaninović JurjevićClinical Hospital Centre Rijeka, Krešimirova ul. 42, 51000 Rijeka, Croatia.ORCID 0000-0001-8359-3910
Štefica DvornikClinical Hospital Centre Rijeka, Krešimirova ul. 42, 51000 Rijeka, Croatia.ORCID 0000-0001-5295-7857

Funding

Croatian Science Foundation IP-2018-5049
6 · The paper itself

Abstract

Moderate wine consumption is often associated with healthy lifestyle habits. The role of wine as a healthy drink is mainly due to its bioactive compounds, which differ according to various viticultural and enological factors. The aim of the present study was to observe the differences in bioactive compounds of white and red autochthonous Croatian wines, differing in terms of the grape variety and production technology. Our further aim was to explore the effect of their moderate consumption (200 mL per day) over the course of six weeks on some aspects of health in sixty-six healthy individuals. Participants were divided into eight groups depending on the wines consumed, while one group formed a non-consuming control group. Medical examination and laboratory tests were performed before the start and at the end of the consumption period. Systolic and diastolic blood pressure, total cholesterol, and LDL concentrations decreased. Additionally, an increase in HDL concentrations, and serotonin and dopamine levels, was observed. ALT, ALP, and GGT levels did not significantly increase in consumer groups, although alcohol concentration was relatively high in all the wines. Such results support the beneficial effects of wine-derived bioactive compounds on some health aspects resulting from moderate white and red wine consumption.

Indexed as

autochthonous Croatian winesbioactive compoundshealthmoderate wine consumption

Identifiers

PMID35742003
PMCPMC9222986

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.