Prevalence of Pathogenic Germline

Akiko Abe, Issei Imoto, Shoichiro Tange, Masato Nishimura, Takeshi Iwasa

Open access · goldAbstract read

In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.6field-weighted citation impact, top 29% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

Risk-reducing decisions regarding germlineJournal of medical genetics · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Akiko AbeDepartment of Gynecology, Cancer Institute Hospital of JCFR, Tokyo 135-8550, Japan.ORCID 0000-0002-0241-1319

Issei ImotoAichi Cancer Center Research Institute, Nagoya 464-8681, Japan.ORCID 0000-0002-4150-7938

Shoichiro TangeDepartment of Medical Genome Sciences, Research Institute for Frontier Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.ORCID 0000-0002-2126-6938

Masato NishimuraDepartment of Obstetrics and Gynecology, Tokushima University, Tokushima 770-8503, Japan.

Takeshi IwasaDepartment of Obstetrics and Gynecology, Tokushima University, Tokushima 770-8503, Japan.

Tokushima University · JPAichi Cancer Center · JPSapporo Medical University · JPThe Cancer Institute Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of germline

Indexed as

Carcinoma, Ovarian EpithelialHereditary Breast and Ovarian Cancer SyndromeOvarian NeoplasmsBRCA1 ProteinBRCA2 ProteinFemaleGerm CellsGerm-Line MutationHumansJapanPrevalenceBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, humanBRCA1/2epithelial ovarian cancergermline pathogenic variantshereditary breast and ovarian cancer syndrome (HBOC)

Identifiers

PMID35741847

DOI10.3390/genes13061085

PMCPMC9223158

OpenAlexW4283069385

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.