Evidence map›Paper›PMID 35741705›Full record

ArticleGenes2022

Genetic Variants Involved in the Crystallization Pathway Are Associated with Calcium Nephrolithiasis in the Chinese Han Population.

Lujia Wang, Xiaoling Lin, Zijian Zhou, Yuanyuan Yang, Peng Gao, Zhong Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lujia WangDepartment of Urology, Huashan Hospital & Institute of Urology, Fudan University, Shanghai 200040, China.
Xiaoling LinDepartment of Urology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China.
Zijian ZhouDepartment of Urology, Huashan Hospital & Institute of Urology, Fudan University, Shanghai 200040, China.
Yuanyuan YangDepartment of Urology, Huashan Hospital & Institute of Urology, Fudan University, Shanghai 200040, China.
Peng GaoDepartment of Urology, Huashan Hospital & Institute of Urology, Fudan University, Shanghai 200040, China.
Zhong WuDepartment of Urology, Huashan Hospital & Institute of Urology, Fudan University, Shanghai 200040, China.ORCID 0000-0002-5103-9517
Shanghai Medical College of Fudan University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A genome-wide association analysis study (GWAS) in the Japanese population identified 14 significant loci associated with nephrolithiasis. Besides 4 novel loci related to metabolic traits, the 10 remaining loci were associated with kidney or electrolyte-related traits. We aimed to replicate the association of these loci with calcium nephrolithiasis in the Chinese Han population. A case-control association analysis was conducted involving 691 calcium nephrolithiasis patients and 1008 control subjects. We were able to genotype a total of 11 single-nucleotide polymorphisms (SNPs) previously identified as being correlated with nephrolithiasis in the Japanese population. SNP rs35747824 at

Indexed as

Genome-Wide Association StudyNephrolithiasisCalciumChinaCrystallizationGenetic Predisposition to DiseaseHumansNeoplasm ProteinsPolymorphism, Single NucleotideProtein Disulfide-IsomerasesBCAS1 protein, humanCalciumNeoplasm ProteinsPDILT protein, humanProtein Disulfide-Isomerasescalcium metabolismChinese Han populationcrystallization pathwaynephrolithiasispolymorphism

Identifiers

PMID35741705
PMCPMC9222851
OpenAlexW4281487834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.