Evidence map›Paper›PMID 35741674›Full record

ArticleBrain sciences2022

Synaptic Dysfunction by Mutations in

Marwa Elmasri, James S Lotti, Wajeeha Aziz, Oliver G Steele, Eirini Karachaliou, Kenji Sakimura, Kasper B Hansen, Andrew C Penn

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. A data-driven framework linking the connectome to spatial gene expression gradients inspired by chemoaffinity theory.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Positive modulators ofRSC advances · 2026
    Article
  4. Article
  5. Article
  6. Characterization of Mice Carrying a Neurodevelopmental Disease-Associated GluN2B(L825V) Variant.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  7. Review
  8. Article
  9. Selective Cell-Surface Expression of Triheteromeric NMDA Receptors.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Frontiers in synaptic neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Marwa ElmasriSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.ORCID 0000-0002-2582-7640
James S LottiCenter for Structural and Functional Neuroscience, Center for Biomolecular Structure and Dynamics, Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA.
Wajeeha AzizSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.
Oliver G SteeleSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.
Eirini KarachaliouSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.
Kenji SakimuraDepartment of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585, Japan.
Kasper B HansenCenter for Structural and Functional Neuroscience, Center for Biomolecular Structure and Dynamics, Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA.ORCID 0000-0002-3303-4819
Andrew C PennSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.ORCID 0000-0002-2812-8386
University of Sussex · GBUniversity of Montana · USNiigata University · JP

Funding

Surveillance genome sequencing to detect SARS-CoV-2 virus variants in MontanaP30GM140963 · NIGMS · UNIVERSITY OF MONTANA · PI BOWLER, BRUCE E · 2021 to 2025
$6.9M
Structural and functional investigation of negative allosteric NMDA receptor modulationR01NS097536 · NINDS · UNIVERSITY OF MONTANA · PI Kasper Boe Hansen · 2016 to 2026
$3.4M
Medical Research Council MR/M020746/1NIGMS NIH HHS P30 GM140963NINDS NIH HHS NS097536NINDS NIH HHS R01 NS097536
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

central nervous systemde novo mutationselectrophysiologyionotropic glutamate receptorssynaptic transmission

Identifiers

PMID35741674
PMCPMC9221112
OpenAlexW4282979216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.