Evidence map›Paper›PMID 35741667›Full record

ArticleBrain sciences2022

Selective Probiotic Treatment Positively Modulates the Microbiota-Gut-Brain Axis in the BTBR Mouse Model of Autism.

Angela Pochakom, Chunlong Mu, Jong M Rho, Thomas A Tompkins, Shyamchand Mayengbam, Jane Shearer

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  12. Frontiers in microbiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Angela PochakomDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0002-2480-069X
Chunlong MuDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0001-9405-5907
Jong M RhoDepartments of Neurosciences, Pediatrics and Pharmacology, University of California San Diego (UCSD), La Jolla, CA 92093, USA.ORCID 0000-0001-9886-9924
Thomas A TompkinsLallemand Inc., Lallemand Bio-Ingredients, Montreal, QC H1W 2N8, Canada.ORCID 0000-0002-2990-2265
Shyamchand MayengbamDepartment of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1C 5S7, Canada.
Jane ShearerDepartment of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0002-1224-979X
University of Calgary · CALallemand (Canada) · CAMemorial University of Newfoundland · CAUniversity of California San Diego · US

Funding

Alberta Children's Hospital 10022770Natural Sciences and Engineering Research Council RGPIN/04238-2018
6 · The paper itself

Abstract

Recent studies have shown promise for the use of probiotics in modulating behaviour through the microbiota-gut-brain axis. In the present study, we assessed the impact of two probiotic strains in mitigating autism-related symptomology in the BTBR

Indexed as

autismgut microbiotametabolismmitochondriaprobiotics

Identifiers

PMID35741667
PMCPMC9220969
OpenAlexW4282947280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.