Evidence map›Paper›PMID 35741598›Full record

ArticleBrain sciences2022

Uric Acid and Cortisol Levels in Plasma Correlate with Pre-Competition Anxiety in Novice Athletes of Combat Sports.

Luis Fernando Garcia de Oliveira, Tácito Pessoa Souza-Junior, Juliane Jellmayer Fechio, José Alberto Fernandes Gomes-Santos, Ricardo Camões Sampaio, Cristina Vasconcelos Vardaris, Rafael Herling Lambertucci, Marcelo Paes de Barros

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Luis Fernando Garcia de OliveiraInstitute of Physical Activity and Sports Science (ICAFE), Cruzeiro do Sul University, Rua Galvão Bueno 868, São Paulo 01506-000, SP, Brazil.
Tácito Pessoa Souza-JuniorResearch Group on Metabolism, Nutrition and Strength Training (GPMENUTF), Campus Politécnico, Federal University of Paraná (UFPR), Rua Coronel Francisco Heráclito dos Santos 210, Curitiba 81531-980, PR, Brazil.
Juliane Jellmayer FechioSantos Football Club, Rua Princesa Isabel s/n, Santos 11075-500, SP, Brazil.
José Alberto Fernandes Gomes-SantosInstitute of Physical Activity and Sports Science (ICAFE), Cruzeiro do Sul University, Rua Galvão Bueno 868, São Paulo 01506-000, SP, Brazil.
Ricardo Camões SampaioInstitute of Physical Activity and Sports Science (ICAFE), Cruzeiro do Sul University, Rua Galvão Bueno 868, São Paulo 01506-000, SP, Brazil.
Cristina Vasconcelos VardarisInstitute of Physical Activity and Sports Science (ICAFE), Cruzeiro do Sul University, Rua Galvão Bueno 868, São Paulo 01506-000, SP, Brazil.
Rafael Herling LambertucciDepartment of Human Movement Sciences, Federal University of São Paulo (UNIFESP), Rua Silva Jardim 136, Santos 11015-020, SP, Brazil.
Marcelo Paes de BarrosInstitute of Physical Activity and Sports Science (ICAFE), Cruzeiro do Sul University, Rua Galvão Bueno 868, São Paulo 01506-000, SP, Brazil.ORCID 0000-0003-3565-8331
Universidade Cruzeiro do Sul · BRCentro Universitário Nossa Senhora do Patrocínio · BRUniversidade Católica de Santos · BRUniversidade Federal de São Paulo · BRUniversidade Federal do Paraná · BR

Funding

National Council for Scientific and Technological Development 305818/2018-0National Council for Scientific and Technological Development 311839/2021-5São Paulo Research Foundation 2017/06032-2São Paulo Research Foundation 2019/02347-4
6 · The paper itself

Abstract

Pre-competition anxiety is very prevalent in novice athletes, causing stress and drastic decreases in their performances. Cortisol plays a central role in the psychosomatic responses to stress and also in the physiology of strenuous exercise. Growing evidence links uric acid, an endogenous antioxidant, with oxidative stress and anxiety, as observed in many depressive-related disorders. We here compared anxiety inventory scores (BAI and CSAI-2), cortisol and biomarkers of oxidative stress in the plasma of novice combat athletes (white and blue belts) before and after their first official national competition, when levels of stress are presumably high. Although the novice fighters did not reveal high indexes of anxiety on questionnaires, significant correlations were confirmed between cortisol and cognitive anxiety (Pearson’s r = 0.766, p-value = 0.002, and a ‘strong’ Bayesian inference; BF10 = 22.17) and between pre-post changes of plasmatic uric acid and somatic anxiety (r = 0.804, p < 0.001, and ‘very strong’ inference; BF10 = 46.52). To our knowledge, this is the first study to report such strong correlations between uric acid and pre-competition anxiety in novice combat athletes. The cause-consequence association between these indexes cannot be directly inferred here, although the interplay between uric acid and anxiety deserves further investigation.

Indexed as

antioxidantdepressionexercisefree radicalglucocorticoidjiu-jitsumoodmotivationoxidative stresssteroids

Identifiers

PMID35741598
PMCPMC9221204
OpenAlexW4281791322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.