ReviewBiology2022
The ABC Model of Happiness-Neurobiological Aspects of Motivation and Positive Mood, and Their Dynamic Changes through Practice, the Course of Life.
Review in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Work-family balance and childcare: The missing link in the lives of working mothers: A letter to editor.International journal of reproductive biomedicine · 2026Article
- The Anatomical and Evolutionary Impact of Pain, Pleasure, Motivation, and Cognition: Integrating Energy Metabolism and the Mind-Body BERN (Behavior, Exercise, Relaxation, and Nutrition) Framework.International journal of molecular sciences · 2025Review
- Mindfulness-Based Cognitive Therapy in Clinical Practice: A Systematic Review of Neurocognitive Outcomes and Applications for Mental Health and Well-Being.Journal of clinical medicine · 2025Review
- Perceived health, quality of life and happiness among older professional artisans in a UNESCO Creative City of crafts and folk art.Frontiers in psychology · 2025Article
- Imaging joy with generalized slice dithered enhanced resolution and SWAT reconstruction: 3T high spatial-temporal resolution fMRI.Frontiers in neuroimaging · 2025Article
- Multidimensional impact of sport types on the psychological well-being of student athletes: A multivariate investigation.Heliyon · 2024Article
- Validation of the Italian version of the Neuroception of Psychological Safety Scale (NPSS).Heliyon · 2024Article
- Validation and Psychometric Properties of the Italian Version of the Unconditional Self-Kindness Scale (USKS).International journal of environmental research and public health · 2023Article
- Mobility Coupled with Motivation Promotes Survival: The Evolution of Cognition as an Adaptive Strategy.Biology · 2023Review
- Understanding health behavior change by motivation and reward mechanisms: a review of the literature.Frontiers in behavioral neuroscience · 2023Review
- The BERN Framework of Mind-Body Medicine: Integrating Self-Care, Health Promotion, Resilience, and Applied Neuroscience.Frontiers in integrative neuroscience · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHappiness is a feeling, an immediate experience, not a cognitive construct. It is based on activity in the brain's neurobiological reward and motivation systems, which have been retained in evolution. This conceptual review provides an overview of the basic neurobiological principles behind happiness phenomena and proposes a framework for further classification.
resultsThree neurobiologically distinct types of happiness exist: (A) wanting, (B) avoiding, and (C) non-wanting. Behind these types lies a dynamic gradation, ranging from the more youthful anticipation, pleasure and ecstasy (A), to stress processing, escape and relief (B) as we find them accentuated in the middle-aged, to deep satisfaction, quiescence and inner joy (C), which is particularly attributed to older people. As a result, the development of happiness and satisfaction over the course of life typically takes the form of a U-curve. DISCUSSION: The outlined triad and dynamic of happiness leads to the paradoxical finding that the elderly seem to be the happiest-a phenomenon that is termed "satisfaction paradox". This assumed change in happiness and contentment over the life span, which includes an increasing "emancipation" from the idea of good health as a mandatory prerequisite for happiness and contentment, can itself be changed-it is trainable.
conclusionsPrograms for mindfulness, contemplation, or stress reduction, including positive psychology and mind-body/behavioral medicine training, seem to be capable of influencing the course happiness over time: Happiness can be shaped through practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.